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Kaley Cuoco
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Kaley Cuoco
Cuoco in July 2017
Born
Kaley Christine Cuoco
(1985-11-30) November 30, 1985 (age 32)
Camarillo, California, U.S.
Other names
Kaley Cuoco-Sweeting
Occupation
Actress
Years active
1992–present
Spouse(s)
Ryan Sweeting (m. 2013; div. 2016)
Kaley Christine Cuoco (/ˈkeɪli ˈkwoʊkoʊ/ KAY-lee KWOH-koh; born November 30, 1985)[1] is an American actress. After a series of supporting film and television roles in the late 1990s, she landed her breakthrough role as Bridget Hennessy on the ABC sitcom 8 Simple Rules, on which she starred from 2002 to 2005. Thereafter, Cuoco appeared as Billie Jenkins on the final season of the television series Charmed (2005–2006). Since 2007, she has starred as Penny on the CBS sitcom The Big Bang Theory, for which she has received Satellite, Critics' Choice, and People's Choice Awards. Cuoco's film work includes roles in To Be Fat like Me (2007), Hop (2011) and Authors Anonymous (2014). She received a star on the Hollywood Walk of Fame in 2014.[2] In October 2017, Cuoco founded Yes, Norman Productions.
Contents
[hide]
1 Early life
2 Career
3 Personal life
4 Filmography
4.1 Film
4.2 Television
5 Awards and nominations
6 References
7 External links
Early life
Cuoco was born in Camarillo, California, the elder daughter of Layne Ann (Wingate), a homemaker, and Gary Carmine Cuoco, a realtor.[3] Her father is of Italian descent while her mother is of English and German ancestry.[4] Her sister, Briana, competed on the fifth season of The Voice. As a child, Cuoco was a regionally ranked amateur tennis player,[5] a sport she took up when she was 3 years old. She stopped playing at the age of 16.[6]
Career
Cuoco made her first feature film appearance as the young Karin Carter in the 1995 action thriller Virtuosity.[7] From 2000 to 2001, Cuoco appeared on the CBS sitcom Ladies Man and in 2000 she portrayed former The Brady Bunch star Maureen McCormick in the TV movie Growing Up Brady as well as starring in the Disney Channel original film Alley Cats Strike. In September 2002, Cuoco began a starring role as Bridget Hennessy on the ABC sitcom 8 Simple Rules. Bridget was the oldest child, despite Cuoco being six years younger than Amy Davidson, who played her younger sister. Because of low ratings, ABC canceled the series on May 17, 2005.
Cuoco at the San Diego Comic-Con in July 2009
In addition to the final season of 8 Simple Rules, Cuoco had starring roles on the NBC miniseries 10.5, the ABC Family original movie Crimes of Fashion, the independent film Debating Robert Lee,[8] and in the film The Hollow at the same time She also voiced the character of Brandy Harrington, a 14-year-old anthropomorphic mixed-breed dog, on the Disney Channel cartoon Brandy and Mr. Whiskers. Cuoco voiced the character of Kirstee Smith in Bratz from 2004 to 2005. In the eighth season of the TV show Charmed, Cuoco appeared as Billie Jenkins, a powerful young witch with the powers of telekinesis and projection. Executive producer Brad Kern stated that Cuoco's character was initially brought in as a possible spin-off.
In September 2007, Cuoco began starring in the CBS sitcom The Big Bang Theory, playing Penny, a Cheesecake Factory employee and aspiring actress who lives across the hall from physicists Dr. Leonard Hofstadter and Dr. Sheldon Cooper. Prior to the 2010–2011 season, she earned $60,000 an episode for the series, the same as her co-stars. In 2010, the cast negotiated a raise for each actor to make $200,000 per episode.[9] On September 13, 2010, she broke her leg in a horse-riding accident and missed two episodes of the series.[10] In late October 2012, Cuoco enlisted the help of her sister Briana to organize a flash mob on the set of the show, in which she and the cast and crew surprised the studio audience by suddenly lip syncing and dancing to Carly Rae Jepsen's song "Call Me Maybe". A video of the event was posted on YouTube and became a viral success.[11][12] A clip from the performance was also played during Cuoco's January 8, 2013 appearance on the late night talk show Conan.[13] As of August 2014, Cuoco and her co-stars from The Big Bang Theory Johnny Galecki and Jim Parsons, each earn an estimated $1 million per episode.[14]
Cuoco at PaleyFest in March 2013
Cuoco starred in the Lifetime film To Be Fat like Me, which premiered on January 8, 2007.[15] She played a minor role in the Prison Break episodes "The Message" and "Chicago", as well as starring in the comedy horror spoof Killer Movie in 2008. She also appeared in the 2010 film The Penthouse. In 2011, Cuoco appeared in Allure magazine's annual "Naked Truth" feature.[16] That same year, she appeared in the films Hop and The Last Ride.[17] She was also chosen to host the Teen Choice Awards in 2011,[18] as well as the People's Choice Awards in 2012 and 2013.[19][20] Cuoco is a regular on Priceline.com commercials as the daughter of William Shatner's character.[21]
In October 2017, Cuoco founded Yes, Norman Productions, a film and television production company which entered an exclusive multi-year first look production deal with Warner Bros. Television. The company optioned the rights to The Flight Attendant, a book written by author Chris Bohjalian, which will be developed into an limited series, with Cuoco to star and executive produce.[22]
Personal life
While working on The Big Bang Theory, Cuoco privately dated co-star Johnny Galecki for roughly two years until December 2009, while their characters on the show were also dating. She told CBS Watch in September 2010 that they have remained on good terms since ending their relationship.[23] She became engaged to addiction specialist Josh Resnik in October 2011, but they ended their engagement by March 2012.[24] Cuoco subsequently became engaged to professional tennis player Ryan Sweeting in September 2013, after three months of dating. They married on December 31, 2013, in Santa Susana, California.[25] On September 25, 2015, it was announced that the two decided to divorce.[26] The divorce was finalized in May 2016.[27] Following the split, she began dating equestrian Karl Cook in late 2015.[28] They became engaged on November 30, 2017, Cuoco's 32nd birthday.[29]
Cuoco received significant media attention surrounding a remark she made in an interview with Redbook magazine. When asked if she considered herself a feminist, Cuoco responded:
Is it bad if I say no? I was never that feminist girl demanding equality, but maybe that's because I've never really faced inequality...I cook for Ryan five nights a week: it makes me feel like a housewife. I love that. I know it sounds old-fashioned, but I like the idea of women taking care of their men.[30][31]
In subsequent interviews, Cuoco has apologized for and retracted these statements, telling Cosmopolitan magazine, "of course I'm a fucking feminist. Look at me. I bleed feminism."[32][33]
Filmography
Film
Year
Title
Role
Notes
1992 Quicksand: No Escape Connie Reinhardt
1995 Virtuosity Karin Carter
1997 Picture Perfect Little girl
1997 Toothless Lori
1998 Mr. Murder Charlotte Stillwater
2000 Alley Cats Strike Elisa Bowers
2000 Growing Up Brady Maureen McCormick
2000 Can't Be Heaven Teresa Powers
2003 Merry Mickey Celebration, AA Merry Mickey Celebration Herself
2004 Debating Robert Lee Maralee Rodgers
2004 Crimes of Fashion Brooke Sarto
2004 Hollow, TheThe Hollow Karen
2005 Lucky 13 Sarah Baker
2006 Separated at Worth Gabby
2006 Wasted Katie Cooning
2006 Bratz: Passion 4 Fashion – Diamondz Kirstee Smith Voice
2007 To Be Fat like Me Alyson Schmidt
2007 Cougar Club Amanda
2008 Killer Movie Blanca Champion
2010 Penthouse, TheThe Penthouse Erica Roc
2011 Hop Samantha O'Hare
2011 Last Ride, TheThe Last Ride Wanda
2014 Authors Anonymous Hannah Rinaldi
2015 The Wedding Ringer Gretchen Palmer
2015 Burning Bodhi Katy
2015 Alvin and the Chipmunks: The Road Chip Eleanor Voice
2016 Why Him? Justine (AI) Voice
2017 Handsome: A Netflix Mystery Movie Herself
Television
Year
Title
Role
Notes
1994 My So-Called Life Young Angela Chase Episode: "Father Figures"
1994 Northern Exposure Miranda Episode: "Hello, I Love You"
1996 Ellen Little Ellen Morgan Episode: "The Bubble Gum Incident"
2000 Don't Forget Your Toothbrush Ashley Episode: "12 March 2000"
2000 Homewood PI Lauren Crane Episode: "Pilot"
2000–01 Ladies Man Bonnie Stiles Main role (Season 2); 8 episodes
2001 7th Heaven Lynn Episode: "Relationships"
2002 First Monday Alyssa Episode: "Pilot"
2002 Ellen Show, TheThe Ellen Show Vanessa Episode: "Shallow Gal"
2002 Nightmare Room, TheThe Nightmare Room Kristin Ferris Episode: "My Name is Evil"
2002–05 8 Simple Rules Bridget Hennessy Main role; 76 episodes
2004 The Help Carly Michaels Episode: "Pilot"
2004 Complete Savages Erin Episode: "For Whom the Cell Tolls"
2004 Punk'd Herself Episode: "9 May 2004"
2004 10.5 Amanda Williams Main role; 2 episodes
2004–06 Brandy & Mr. Whiskers Brandy Harrington (voice) Main role; 77 episodes
2005–06 Bratz Kirstee Smith (voice) Main role (Season 1); 17 episodes
2005–07 Loonatics Unleashed Paula Hayes / Weather Vane (voice) Recurring role; 3 episodes
2005–06 Charmed Billie Jenkins Main role (Season 8); 22 episodes
2006 Secrets of a Small Town Misty Anders Unsold ABC pilot
2007 Prison Break Sasha Murray Episodes: "The Message" and "Chicago"
2007–present Big Bang Theory, TheThe Big Bang Theory Penny Main role
2012 Peterson: Untouchable, DrewDrew Peterson: Untouchable Stacy Peterson Television film
2016 Comedy Bang! Bang! Herself Episode: "Kaley Cuoco Wears a Black Blazer and Slip on Sneakers"
Awards and nominations
Year
Award
Category
Work
Result
1993 Young Artist Award Best Young Actress in a Cable Movie Quicksand: No Escape Nominated
2000 YoungStar Award Best Young Actress in a Mini-Series/Made for TV Film Growing Up Brady Nominated
2003 Young Artist Awards Best Performance in a TV Series (Comedy or Drama) – Leading Young Actress 8 Simple Rules Nominated
2003 Teen Choice Awards Choice TV Actress: Comedy 8 Simple Rules Nominated
2003 Teen Choice Awards Choice TV Breakout Star: Female 8 Simple Rules Won
2004 Teen Choice Awards Choice TV Actress: Comedy 8 Simple Rules Nominated
2004 Young Artist Awards Best Young Adult Performer in a Teenage Role 8 Simple Rules Nominated
2010 Teen Choice Awards Choice TV Actress: Comedy The Big Bang Theory Nominated
2011 Teen Choice Awards Choice TV Actress: Comedy The Big Bang Theory Nominated
2012 People's Choice Awards Favorite TV Comedy Actress The Big Bang Theory Nominated
2012 Teen Choice Awards Choice TV Actress: Comedy The Big Bang Theory Nominated
2012 Satellite Award Best Actress – Television Series Musical or Comedy[34] The Big Bang Theory Won
2013 Teen Choice Awards Choice TV Actress: Comedy The Big Bang Theory Nominated
2013 People's Choice Awards Favorite TV Comedy Actress The Big Bang Theory Nominated
2013 Critics' Choice Television Award Best Supporting Actress in a Comedy Series (tied with Eden Sher) The Big Bang Theory Won
2014 People's Choice Awards Favorite TV Comedy Actress The Big Bang Theory Won
2014 Kids' Choice Awards Favorite Funny Star The Big Bang Theory Nominated
2014 Critics' Choice Television Award Best Supporting Actress in a Comedy Series The Big Bang Theory Nominated
2015 People's Choice Awards Favorite Comedic TV Actress The Big Bang Theory Won
2015 Kids' Choice Awards Favorite TV Actress The Big Bang Theory Nominated
2015 Teen Choice Awards Choice TV Actress: Comedy The Big Bang Theory Nominated
2016 Golden Raspberry Awards Worst Supporting Actress The Wedding Ringer Won
References
Jump up ^ "8 Interesting Facts About Kaley Cuoco-Sweeting: Actor Spotlight". CBS. Retrieved May 15, 2016.
Jump up ^ Lombardi, Ken (October 30, 2014). "Kaley Cuoco-Sweeting gets emotional over Hollywood Walk of Fame star". CBS News. Retrieved November 3, 2014.
Jump up ^ "Kaley Cuoco". Yahoo!. Retrieved November 17, 2012.
Jump up ^ "5 Things You Don't Know About Kaley Cuoco". ET Online. Archived from the original on January 6, 2014. Retrieved October 2, 2013.
Jump up ^ "Southern California Tennis Association 1998 Year-End Junior Rankings – Girls'_14_Singles". californiatennis.com. Retrieved October 7, 2012. No. 54 in Girls' 14 Singles.
Jump up ^ Acuna, Kirsten (March 2, 2012). "25 Things You Don't Know About Newly Single Kaley Cuoco—CBS' 'Big Bang Theory' Sweetheart". Business Insider. Retrieved October 7, 2012. Cuoco has been an ace in Hollywood and on the tennis court, playing the sport since she was three years old. She finally made the full switch to acting in 2002
Jump up ^ Entertainment Tonight. CBS. November 30, 2012.
Jump up ^ "Debating Robert Lee (2006)". Rotten Tomatoes. Retrieved August 29, 2014.
Jump up ^ "Kaley Cuoco". kaleycuoco.org. Archived from the original on September 21, 2010. Retrieved September 15, 2010.
Jump up ^ Masters, Megan (October 12, 2010). "Kaley Cuoco Returns to Big Bang Theory After Injury as a-Pregnant Amputee Bartender?!". E!. Retrieved November 7, 2010.
Jump up ^ Ratledge, Ingela (December 3, 2012) "Big Bang's Flash Mob Mentality". TV Guide. p. 6
Jump up ^ "The Big Bang Theory Flash mob! [Full version compilation]". NommiXproductions. YouTube. November 16, 2012. Retrieved November 28, 2012.
Jump up ^ "The Guy Who Drove a Hummer and Wasn't a Total A-Hole". Conan. Season 3. Episode 25. January 8, 2013. TBS.
Jump up ^ "Big Bang Theory stars sign new contracts". BBC News. Retrieved August 4, 2014.
Jump up ^ "Movies — To Be Fat Like Me". lifetimetv.com. Archived from the original on March 3, 2007. Retrieved March 18, 2007.
Jump up ^ Brown, Robyn (May 2011). "The Naked Truth: 4 Celebrities Go Nude for Allure". Allure. Retrieved July 4, 2011.
Jump up ^ "Kaley Cuoco Signs For "I Hop," "Last Ride" – March 31, 2010". Dark Horizons. Retrieved May 7, 2010.
Jump up ^ "Kaley Cuoco to Host 2011 Teen Choice Awards". J-14. Retrieved July 28, 2011.
Jump up ^ "Kaley Cuoco to Host 2012 People's Choice Awards". People's Choice. Archived from the original on October 1, 2012. Retrieved October 9, 2012.
Jump up ^ "Kaley Cuoco to host People's Choice Awards". Entertainment Weekly. Retrieved February 27, 2012.
Jump up ^ "Kaley Cuoco joins Shatner in Priceline ads". USA Today. January 9, 2013. Retrieved April 26, 2013.
Jump up ^ Andreeva, Nellie (27 October 2017). "Kaley Cuoco Launches Company, Inks Pod Deal With Warner Bros. TV & Set First Project – Limited Series She Would Star In". Deadline.
Jump up ^ Morgan, Hudson (September 2010). "Justify Her Love". CBS Watch. Archived from the original on February 7, 2014.
Jump up ^ Weiner, David (March 2, 2012). "ET Exclusive: Kaley Cuoco No Longer Engaged". ET Online.
Jump up ^ "'Big Bang Theory' star Kaley Cuoco gets married". Associated Press via Newsday. Archived from the original on January 2, 2014. Retrieved January 4, 2014.
Jump up ^ Krauser, Emily (September 25, 2015). "Kaley Cuoco Divorcing Ryan Sweeting After 21 Months of Marriage". Entertainment Tonight.
Jump up ^ Ungerman, Alex (May 9, 2016). "Kaley Cuoco Finalizes Divorce From Ryan Sweeting, Actress to Pay $165,000 in Spousal Support". Entertainment Tonight. Retrieved May 10, 2016.
Jump up ^ Kile, Meredith B. (December 18, 2016). "EXCLUSIVE: Kaley Cuoco Gushes Over 'Perfect' Boyfriend Karl Cook at 'Why Him?' Premiere". Entertainment Tonight. Retrieved March 10, 2017.
Jump up ^ Mizoguchi, Karen (November 30, 2017). "Kaley Cuoco Is Engaged to Boyfriend Karl Cook — Watch Her Emotional Reaction to the Proposal". People. Retrieved November 30, 2017.
Jump up ^ "Kaley Cuoco-Sweeting Does Not Consider Herself a Feminist: I Love Feeling Like a Housewife". Dec 30, 2014. Retrieved March 30, 2017.
Jump up ^ "Kaley Cuoco: I'm Not a Feminist and I Love Feeling Like a Housewife". Dec 30, 2014. Retrieved March 30, 2017.
Jump up ^ "Kaley Cuoco-Sweeting apologizes for saying she's not a feminist". Jan 2, 2015. Retrieved March 30, 2017.
Jump up ^ "KKaley Cuoco: "Of Course I'm a F*cking Feminist"". Mar 4, 2016. Retrieved March 30, 2017.
Jump up ^ Kilday, Gregg. "'Silver Linings Playbook' Wins Five Satellite Awards, Including Best Picture". The Hollywood Reporter. Retrieved April 24, 2016.
External links
Wikimedia Commons has media related to Kaley Cuoco.
Kaley Cuoco on IMDb
Kaley Cuoco at Rotten Tomatoes
Media offices
Preceded by
Queen Latifah People's Choice Awards host
2012–2013 Succeeded by
Beth Behrs & Kat Dennings
Preceded by
Katy Perry Teen Choice Awards host
2011 Succeeded by
Demi Lovato & Kevin McHale
[show]
Awards for Kaley Cuoco
[show]
v
t
e
Critics' Choice Television Award for Best Supporting Actress in a Comedy Series
Busy Philipps (2011)
Julie Bowen (2012)
Kaley Cuoco / Eden Sher (2013)
Allison Janney / Kate Mulgrew (2014)
Allison Janney (2015)
Mayim Bialik (2016)
Jane Krakowski (2016)
Mayim Bialik (2017)
[show]
v
t
e
Satellite Award for Best Actress – Television Series Musical or Comedy
Jane Curtin (1996)
Tracey Ullman (1997)
Ellen DeGeneres (1998)
Illeana Douglas (1999)
Lisa Kudrow (2000)
Debra Messing (2001)
Debra Messing (2002)
Jane Kaczmarek (2003)
Portia de Rossi (2004)
Felicity Huffman / Mary-Louise Parker (2005)
Marcia Cross (2006)
America Ferrera (2007)
Tracey Ullman (2008)
Lea Michele (2009)
Laura Linney (2010)
Martha Plimpton (2011)
Kaley Cuoco (2012)
Taylor Schilling (2013)
Mindy Kaling (2014)
Taylor Schilling (2015)
Taylor Schilling (2016)
Authority control
WorldCat Identities
VIAF: 120774532
LCCN: no2009114716
ISNI: 0000 0001 1086 3852
GND: 101457420X
SUDOC: 157441261
BNF: cb16205740q (data)
BNE: XX5154775
Retrieved from "https://en.wikipedia.org/w/index.php?title=Kaley_Cuoco&oldid=822042536"
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text:
Endoplasmic reticulum
From Wikipedia, the free encyclopedia
Jump to: navigation, search
Cell biology
The animal cell
Components of a typical animal cell:
Nucleolus
Nucleus
Ribosome (little dots)
Vesicle
Rough endoplasmic reticulum
Golgi apparatus (or "Golgi body")
Cytoskeleton
Smooth endoplasmic reticulum
Mitochondrion
Vacuole
Cytosol (fluid that contains organelles, comprising the cytoplasm)
Lysosome
Centrosome
Cell membrane
Micrograph of rough endoplasmic reticulum network around the nucleus (shown in lower right-hand side of the picture). Dark small circles in the network are mitochondria.
The endoplasmic reticulum (ER) is a type of organelle found in eukaryotic cells that forms an interconnected network of flattened, membrane-enclosed sacs or tube-like structures known as cisternae. The membranes of the ER are continuous with the outer nuclear membrane. The endoplasmic reticulum occurs in most types of eukaryotic cells, but is absent from red blood cells and spermatozoa. There are two types of endoplasmic reticulum: rough and smooth. The outer (cytosolic) face of the rough endoplasmic reticulum is studded with ribosomes that are the sites of protein synthesis. The rough endoplasmic reticulum is especially prominent in cells such as hepatocytes. The smooth endoplasmic reticulum lacks ribosomes and functions in lipid manufacture and metabolism, the production of steroid hormones, and detoxification.[1] The smooth ER is especially abundant in mammalian liver and gonad cells. The lacy membranes of the endoplasmic reticulum were first seen in 1945 using electron microscopy.
Contents
[hide]
1 History
2 Structure
2.1 Rough endoplasmic reticulum
2.2 Smooth endoplasmic reticulum
2.2.1 Sarcoplasmic reticulum
3 Functions
3.1 Protein transport
4 Clinical significance
5 References
6 External links
History[edit]
The lacy membranes of the endoplasmic reticulum were first seen in 1945 by Keith R. Porter, Albert Claude, Brody Meskers and Ernest F. Fullam, using electron microscopy.[2] The word reticulum, which means "network", was applied to describe this fabric of membranes.
Structure[edit]
1 Nucleus 2 Nuclear pore 3 Rough endoplasmic reticulum (RER) 4 Smooth endoplasmic reticulum (SER) 5 Ribosome on the rough ER 6 Proteins that are transported 7 Transport vesicle 8 Golgi apparatus 9 Cis face of the Golgi apparatus 10 Trans face of the Golgi apparatus 11 Cisternae of the Golgi apparatus
3D rendering of endoplasmic reticulum
The general structure of the endoplasmic reticulum is a network of membranes called cisternae. These sac-like structures are held together by the cytoskeleton. The phospholipid membrane encloses the cisternal space (or lumen), which is continuous with the perinuclear space but separate from the cytosol. The functions of the endoplasmic reticulum can be summarized as the synthesis and export of proteins and membrane lipids, but varies between ER and cell type and cell function. The quantity of both rough and smooth endoplasmic reticulum in a cell can slowly interchange from one type to the other, depending on the changing metabolic activities of the cell. Transformation can include embedding of new proteins in membrane as well as structural changes. Changes in protein content may occur without noticeable structural changes.[3][4][citation needed]
Rough endoplasmic reticulum[edit]
An animation showing how a protein destined for the secretory pathway is synthesized into the rough endoplasmic reticulum (which appears at upper right in animation when approximately half of animation is done). The total animation time is about 2 minutes.
The surface of the rough endoplasmic reticulum (often abbreviated RER or Rough ER) (also called granular endoplasmic reticulum) is studded with protein-manufacturing ribosomes giving it a "rough" appearance (hence its name).[5] The binding site of the ribosome on the rough endoplasmic reticulum is the translocon.[6] However, the ribosomes are not a stable part of this organelle's structure as they are constantly being bound and released from the membrane. A ribosome only binds to the RER once a specific protein-nucleic acid complex forms in the cytosol. This special complex forms when a free ribosome begins translating the mRNA of a protein destined for the secretory pathway.[7] The first 5–30 amino acids polymerized encode a signal peptide, a molecular message that is recognized and bound by a signal recognition particle (SRP). Translation pauses and the ribosome complex binds to the RER translocon where translation continues with the nascent (new) protein forming into the RER lumen and/or membrane. The protein is processed in the ER lumen by an enzyme (a signal peptidase), which removes the signal peptide. Ribosomes at this point may be released back into the cytosol; however, non-translating ribosomes are also known to stay associated with translocons.[8]
The membrane of the rough endoplasmic reticulum forms large double membrane sheets that are located near, and continuous with, the outer layer of the nuclear envelope.[9] The double membrane sheets are stacked and connected through several right or left-handed helical ramps, the so-called Terasaki ramps, giving rise to a structure resembling a multi-storey car park.[10][11] Although there is no continuous membrane between the endoplasmic reticulum and the Golgi apparatus, membrane-bound transport vesicles shuttle proteins between these two compartments.[12] Vesicles are surrounded by coating proteins called COPI and COPII. COPII targets vesicles to the Golgi apparatus and COPI marks them to be brought back to the rough endoplasmic reticulum. The rough endoplasmic reticulum works in concert with the Golgi complex to target new proteins to their proper destinations. A second method of transport out of the endoplasmic reticulum involves areas called membrane contact sites, where the membranes of the endoplasmic reticulum and other organelles are held closely together, allowing the transfer of lipids and other small molecules.[13][14]
The rough endoplasmic reticulum is key in multiple functions:
Manufacture of lysosomal enzymes with a mannose-6-phosphate marker added in the cis-Golgi network.[citation needed]
Manufacture of secreted proteins, either secreted constitutively with no tag or secreted in a regulatory manner involving clathrin and paired basic amino acids in the signal peptide.
Integral membrane proteins that stay embedded in the membrane as vesicles exit and bind to new membranes. Rab proteins are key in targeting the membrane; SNAP and SNARE proteins are key in the fusion event.
Initial glycosylation as assembly continues. This is N-linked (O-linking occurs in the Golgi).
N-linked glycosylation: If the protein is properly folded, Oligosaccharyltransferase recognizes the AA sequence NXS or NXT (with the S/T residue phosphorylated) and adds a 14-sugar backbone (2-N-acetylglucosamine, 9-branching mannose, and 3-glucose at the end) to the side-chain nitrogen of Asn.
Smooth endoplasmic reticulum[edit]
Electromicrograph showing smooth ER (arrow) in mouse tissue, at 110,510 x magnification.
In most cells the smooth endoplasmic reticulum (abbreviated SER) is scarce. Instead there are areas where the ER is partly smooth and partly rough, this area is called the transitional ER. The transitional ER gets its name because it contains ER exit sites. These are areas where the transport vesicles that contain lipids and proteins made in the ER, detach from the ER and start moving to the Golgi apparatus. Specialized cells can have a lot of smooth endoplasmic reticulum and in these cells the smooth ER has many functions.[15] It synthesizes lipids, phospholipids, and steroids. Cells which secrete these products, such as those in the testes, ovaries, and sebaceous glands have an abundance of smooth endoplasmic reticulum.[16] It also carries out the metabolism of carbohydrates, detoxification of natural metabolism products and of alcohol and drugs, attachment of receptors on cell membrane proteins, and steroid metabolism.[17] In muscle cells, it regulates calcium ion concentration. Smooth endoplasmic reticulum is found in a variety of cell types (both animal and plant), and it serves different functions in each. The smooth endoplasmic reticulum also contains the enzyme glucose-6-phosphatase, which converts glucose-6-phosphate to glucose, a step in gluconeogenesis. It is connected to the nuclear envelope and consists of tubules that are located near the cell periphery. These tubes sometimes branch forming a network that is reticular in appearance.[9] In some cells, there are dilated areas like the sacs of rough endoplasmic reticulum. The network of smooth endoplasmic reticulum allows for an increased surface area to be devoted to the action or storage of key enzymes and the products of these enzymes.
Sarcoplasmic reticulum[edit]
Main article: Sarcoplasmic reticulum
See also: Calcium-induced calcium release
Skeletal muscle fiber, with sarcoplasmic reticulum colored in blue.
The sarcoplasmic reticulum (SR), from the Greek σάρξ sarx ("flesh"), is smooth ER found in myocytes. The only structural difference between this organelle and the smooth endoplasmic reticulum is the medley of proteins they have, both bound to their membranes and drifting within the confines of their lumens. This fundamental difference is indicative of their functions: The endoplasmic reticulum synthesizes molecules, while the sarcoplasmic reticulum stores calcium ions and pumps them out into the sarcoplasm when the muscle fiber is stimulated.[18][19] After their release from the sarcoplasmic reticulum, calcium ions interact with contractile proteins that utilize ATP to shorten the muscle fiber. The sarcoplasmic reticulum plays a major role in excitation-contraction coupling.[20]
Functions[edit]
The endoplasmic reticulum serves many general functions, including the folding of protein molecules in sacs called cisternae and the transport of synthesized proteins in vesicles to the Golgi apparatus. Correct folding of newly made proteins is made possible by several endoplasmic reticulum chaperone proteins, including protein disulfide isomerase (PDI), ERp29, the Hsp70 family member BiP/Grp78, calnexin, calreticulin, and the peptidylpropyl isomerase family. Only properly folded proteins are transported from the rough ER to the Golgi apparatus – unfolded proteins cause an unfolded protein response as a stress response in the ER. Disturbances in redox regulation, calcium regulation, glucose deprivation, and viral infection[21] or the over-expression of proteins[22] can lead to endoplasmic reticulum stress response (ER stress), a state in which the folding of proteins slows, leading to an increase in unfolded proteins. This stress is emerging as a potential cause of damage in hypoxia/ischemia, insulin resistance, and other disorders.[23]
Protein transport[edit]
Secretory proteins, mostly glycoproteins, are moved across the endoplasmic reticulum membrane. Proteins that are transported by the endoplasmic reticulum throughout the cell are marked with an address tag called a signal sequence. The N-terminus (one end) of a polypeptide chain (i.e., a protein) contains a few amino acids that work as an address tag, which are removed when the polypeptide reaches its destination. Nascent peptides reach the ER via the translocon, a membrane-embedded multiprotein complex. Proteins that are destined for places outside the endoplasmic reticulum are packed into transport vesicles and moved along the cytoskeleton toward their destination. In human fibroblasts, the ER is always co-distributed with microtubules and the depolymerisation of the latter cause its co-aggregation with mitochondria, which are also associated with the ER.[24]
The endoplasmic reticulum is also part of a protein sorting pathway. It is, in essence, the transportation system of the eukaryotic cell. The majority of its resident proteins are retained within it through a retention motif. This motif is composed of four amino acids at the end of the protein sequence. The most common retention sequences are KDEL for lumen located proteins and KKXX for transmembrane protein.[25] However, variations of KDEL and KKXX do occur, and other sequences can also give rise to endoplasmic reticulum retention. It is not known whether such variation can lead to sub-ER localizations. There are three KDEL (1, 2 and 3) receptors in mammalian cells, and they have a very high degree of sequence identity. The functional differences between these receptors remain to be established.[26]
Clinical significance[edit]
Abnormalities in XBP1 lead to a heightened endoplasmic reticulum stress response and subsequently causes a higher susceptibility for inflammatory processes that may even contribute to Alzheimer's disease.[27] In the colon, XBP1 anomalies have been linked to the inflammatory bowel diseases including Crohn's disease.[28]
The unfolded protein response (UPR) is a cellular stress response related to the endoplasmic reticulum.[29] The UPR is activated in response to an accumulation of unfolded or misfolded proteins in the lumen of the endoplasmic reticulum. The UPR functions to restore normal function of the cell by halting protein translation, degrading misfolded proteins, and activating the signaling pathways that lead to increasing the production of molecular chaperones involved in protein folding. Sustained overactivation of the UPR has been implicated in prion diseases as well as several other neurodegenerative diseases and the inhibition of the UPR could become a treatment for those diseases.[30]
References[edit]
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External links[edit]
Wikimedia Commons has media related to Endoplasmic reticulum.
Lipid and protein composition of Endoplasmic reticulum in OPM database
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Sitti
From Wikipedia, the free encyclopedia
Jump to: navigation, search
Sitti Navarro
Sitti in concert on SM Taytay.
Background information
Birth name
Sitti Katrina Baiddin Navarro
Also known as
Philippines' Queen of Bossa Nova
Born
(1984-11-29) November 29, 1984 (age 33)
Manila, Philippines
Origin
Las Piñas
Genres
Bossa nova, jazz, Pinoy pop
Occupation(s)
Singer, actor
Instruments
Vocals
Years active
2006-present
Labels
Warner Music Group
MCA
Website
www.sittionline.com
Sitti Navarro (born November 29, 1984[1] in Las Piñas), also known as Sitti, is a Filipino bossa nova singer.[2] After releasing her first album, Café Bossa, in 2006, other bossa nova acts in the Philippines followed.[3] Navarro is also featured in the segment "A.S.A.P. Sessionistas" of the variety show ASAP.[4]
Contents
[hide]
1 Early life
2 Personal life
3 Musical career
4 Television work
5 Stage Acting
6 Discography
6.1 Studio albums
6.2 Live albums
6.3 Compilations
7 Filmography
8 Awards
9 References
10 External links
Early life[edit]
Sitti Navarro was born to lawyer Rolando Navarro and Lydia Baiddin, in Manila, Philippines. Sitti is of Samal and Tausūg descent. She identifies herself as being Jama Mapun (Sama Kagayan), one of the Sama-Bajau subgroups in Tawi-Tawi.[5] She graduated from the University of the Philippines Diliman in April 2005 with a degree in Business Economics and was a dean's lister at said university.[6] In high school, she was editor-in-chief of the school paper and graduated as valedictorian of her class.[1]
In college, she was an active member of the AIESEC Local Committee where she was the Vice President for Outgoing Exchange from 2003 to 2004.[7] She was also a member of the Organization of Business Economics Majors (OBEM) in UP Diliman.[citation needed]
Sitti has won two beauty pageant awards: the title of Miss Visayas 2001 in the Miss Travel Girl Pageant, and the first runner-up in the search for "Miss Silka" where she was also named Miss Friendship and Best in Swimwear.[1]
Personal life[edit]
Since tying the knot[citation needed] with fiancé Joey Ramirez last May at a beautiful garden wedding in Baguio City, Bossa Nova Queen Sitti Navarro — who will soon be celebrating her 10th year in the industry — has changed a lot, and we’re not just talking about her civil status.
In a press gathering to launch her latest album Sitti Singles: Bossa Nova Trio (the last album she recorded as a single woman), Sitti talked about her first few months of married life.
She and Joey — a businessman and triathlete — were matched up as blind dates by the cousin of Sitti’s bestfriend who goes biking with her regularly. She thought the two would make a good match, and they did. Since then, according to Sitti, she has noticed that everything in her life has taken on a deeper, richer tone and that includes her music. “Mas may kabuluhan, mas meaningful,” she said, becoming teary-eyed.
“I had no idea that being married could give one such happiness. This is a new chapter in my life looking how they will affect me as a singer and songwriter.”
Musical career[edit]
Since the age of 16,[1] Sitti has been performing gigs at the Hyatt Calesa Bar and others.[8] Although it was her dream to be a TV host, she is now one of the Philippines' newest singers. In 2004, MTV Philippines started "MTV Supahstar: D' Super Search", where Sitti was one of the winners.[9] She also appeared in the group's music videos, showcasing her talents. It led to her recording contract.
Her debut album, Café Bossa, was released in 2006.[3] Four songs have been released': "Tattooed On My Mind", a remake of the D'Sound hit; "Hey Look at the Sun", "I Didn't Know I Was Looking for Love", and "Para Sa Akin". A live album, Sitti Live!, was released in late 2006, and Café Bossa was re-released with a VCD in 2007.
Sitti collaborated with Club Myx to release Sitti in the Mix - The Dense Modesto Remixes, a collection of songs from Café Bossa that were made into dance-electronica songs with the help of DJ Dense Modesto, in mid-2007, before the release of her second album My Bossa Nova, which focuses on more recent songs. My Bossa Nova was re-released in mid-2008 with a VCD of Sitti Live! 2 called My Bossa Nova Live! and is now a certified Platinum album at the moment.
In the third quarter of 2008, Sitti released her first Christmas album, Ngayong Pasko. Unlike her past albums, this album is purely a cover versions album with only one original song, the carrier single and title of the album, Ngayong Pasko. This album also has reached the Gold status in less than a month after its release.
Sitti has also collaborated with Asia's Pop Idol and Romantic Balladeer, Christian Bautista for his album Captured for a duet of the song of the same title. They once again collaborated for Sitti's Christmas album on the song "Baby It's Cold Outside".
In the second quarter of 2009, Sitti released her third studio album entitled "Contagious", which contains an original which was also the carrier single, "Is This Love", co-penned by Andrew Fromm, who also penned Christian Bautista's hit song, "The Way You Look At Me".
On March 8, 2012, she released her fifth studio album, Sitti - Sessions, which spawned two singles; "Sino'ng Mag-aakala" and "Wag Mo Na Munang Sabihin". The album allowed her to experiment with other genres apart from bossa nova.[10]
In the first Tokyo-Manila Jazz and Arts Festival, Sitti announced that her record label's Japanese branch will release one of her albums there, and that the label will decide on its release date.[11] The album, released May 2012 on iTunes and October 2012 in stores, is titled "Bossa Covers".[12]
In 2013, she participated in the Philippines' highly esteemed Elements National Music Camp, where she was mentored by the likes of Ryan Cayabyab, Joey Ayala and Gary Granada, among others.[13]
On June 25, 2013, it was announced that she will be entering the second Philippine Popular Music Festival as an interpreter with Julianne Tarroja for the song called "Pansamantagal" written by Jungee Marcelo.[14]
Television work[edit]
Sitti was also co-host of Pinoy Big Brother Season 2 on Studio 23, alongside Asia Agcaoili, ending with the victory of Beatriz Saw. She is currently the official endorser for Lush Group of Companies, specially for the brands Fruitas, Buko Ni Fruitas and The Mango Farm chains all over the Philippines.
She also ventured into acting in Judy Ann Santos' primetime teleserye, "Isabella", where she portrayed 'Tere', an aspiring lounge singer. Sitti was also featured in ABS-CBN's "Your Song" where her song "Ikaw Lamang" was the single for the episode she acted in with Sam Milby.
She also had a few hosting stints in Studio 23 such as Pinoy Dream Academy and Travel Time.
Sitti is currently a semi-regular on ABS-CBN's top-rating Sunday variety show, ASAP '09. She appears on a segment called ASAP Sessionistas together with MYMP, Aiza Seguerra, Nina, Richard Poon and Duncan Ramos.
Stage Acting[edit]
Sitti was part of "Katy! The Musical" which was staged last December 27, 2008 at Harbor Garden Tent Sofitel Philippine Plaza Manila wherein she played as Mary Walter. Alongside her was KC Concepcion, Jericho Rosales, Mitch Valdez, Dulce, Eugene Villaluz,Rachel Alejandro, Bituin Escalante, Jonalyn Viray, Aicelle Santos, Maricris Garcia, Frenchie Dy, Gian Magdangal, Gab Valenciano and Jennylyn Mercado.[6]
In 2009, Sitti played the role of "Martha" in the Philippine staging of the Tony-award winning, 19th century stage drama Spring Awakening from Atlantis Productions. Spring Awakening was directed by Chari Arespacochaga and features the set design of Tuxqs Rutaquio, choreography by Dexter Santos, costume design by Rajo Laurel, lights design by Voltaire de Jesus and musical direction by Jojo Malferari.[6]
Discography[edit]
Studio albums[edit]
Year
Album details
Certifications
(sales thresholds)
2006 Café Bossa
Released: January 25, 2006
Label: Warner
Format: Vinyl record, digital download, cassette, reel
PHI: 2× Platinum[15]
2007 My Bossa Nova
Released: August 24, 2007
Label: Warner
Format: Vinyl record, digital download, cassette, reel
PHI: Gold[15]
2008 Ngayong Pasko
Released: October 30, 2008
Label: Warner
Format: Vinyl record, digital download, cassette, reel
PHI: Platinum[16]
2009 Contagious
Released: June 26, 2009
Label: Warner
Format: Vinyl record, digital download, cassette, reel
—
2011 Sessions
Released: March 4, 2011
Label: Warner
Format: Vinyl record, digital download, cassette, reel
2012 Bossa Covers
Released: 2012
Label: Warner
Format: Vinyl record, digital download, cassette, reel
2014 Bossa Love
Released: January 18, 2014
Label: MCA
Format: DataPlay, Vinyl record, digital download, cassette, reel, 8 Track
Live albums[edit]
Year
Album details
Certifications
2006 Sitti Live!
Released: September 15, 2006
Label: Warner
Format: Vinyl record, digital download, cassette, reel
PHI: Gold[15]
2008 My Bossa Nova Live!
Released: 2008
Label: Warner
Format: Vinyl record, digital download, cassette, reel
PHI: Platinum[15]
Compilations[edit]
Year
Album details
Certifications
2007 Sitti in the Mix: The Dense Modesto Remixes
Released: 2007
Label: Warner, Club Myx
Format: Vinyl record, digital download, cassette, reel
—
Filmography[edit]
Year
Title
Role
Notes
2006 ASAP Herself 2006—present
Pinoy Dream Academy (season 1) Herself Studio 23 host
2007 Pinoy Big Brother (season 2) Herself Studio 23 host
Ysabella Tere Recurring role
2009 Squalor Indie film
2010 Showtime Herself Guest judge
2012 Angelito: Ang Bagong Yugto Susan Samaniego Special Guest
2016 Unang Hirit Herself Guest Performer
Awards[edit]
This section needs expansion. You can help by adding to it. (May 2014)
Year
Award-Giving Body
Category
Work
Result
2008 GMMSF Box-Office Entertainment Awards Female Recording Artist of the Year[17] Won
References[edit]
^ Jump up to: a b c d "When the city falls in love with Sitti this Valentine's". The Freeman. The Philippine Star. Retrieved 2010-01-21.
Jump up ^ Francisco, Mark (2008-04-14). "Sitti Navarro wows Cagayan de Oro". Sun.Star Cagayan de Oro. Retrieved 2010-01-21.
^ Jump up to: a b "Erik, Sitti in Extraordinary Songs". The Philippine Star. 2009-11-09. Retrieved 2010-01-21.
Jump up ^ "A.S.A.P. Sessionistas at the Big Dome". Philippine Star. 2009-08-23. Retrieved 2010-01-21. </ Losorata, Yugel (2007-09-16). "Sitti up for more conquests". Manila Bulletin. Retrieved 19 December 2012.
Jump up ^ Betonio, Terry (2010-02-09). "Simply Sitti". Sun Star Cagayan de Oro. Retrieved 19 December 2012.
^ Jump up to: a b c Sandiego, Bettina (2009-11-24). "Erik Santos and Sitti Navarro team up for an "Extraordinary" concert, Nov 21". Philippine Entertainment Portal. Retrieved 2010-01-21.
Jump up ^ "Sitti will perform for a charity concert on December 10". 2008-11-08. Retrieved 2010-01-21.
Jump up ^ Torre, Nestor (2002-10-26). "Sleeper Hit". Viewfinder. Philippine Daily Inquirer. Retrieved 2010-01-21.
Jump up ^ "The Supah Concert of the Supahstars". Philippine Daily Inquirer. 2005-04-09. Retrieved 2010-01-21.
Jump up ^ "Sitti - Sessions". iTunes Store. https://itunes.apple.com/au/album/sitti-sessions/id515819498. Retrieved July 6, 2013.
Jump up ^ DZMM (May 26, 2012). "Sitti to release album in Japan". Sitti Online. Retrieved September 19, 2012.
Jump up ^ "Bossa Covers by Sitti". iTunes. Retrieved November 23, 2012.
Jump up ^ http://elementsmusiccamp.com.ph/index.php/campers/baiddin-sitti-katrina/
Jump up ^ "Christian Bautista, Karylle and other singers to interpret Philpop 2013 entries". Philippine Entertainment Portal. June 5, 2013. Retrieved June 26, 2013.
^ Jump up to: a b c d "Awards > Album Recognition". SittiOnline.com. Retrieved 2010-12-16.
Jump up ^ DIRECTLINE, Boy Abunda (January 5, 2009). "Sitti wants to bring ethnic music to the world". The Philippine Star. Retrieved 2010-12-16.
Jump up ^ "The 38th Box-Office Entertainment Awards (Part 2)". Pep.ph. Retrieved 2014-05-24.
External links[edit]
Official site
Sitti at Multiply
Sitti on IMDb
Authority control
MusicBrainz: 09b52803-c7ce-483a-a83c-e215781dc29e
Retrieved from "https://en.wikipedia.org/w/index.php?title=Sitti&oldid=813795157"
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text:
Just Fine
From Wikipedia, the free encyclopedia
Jump to: navigation, search
"Just Fine"
Single by Mary J. Blige
from the album Growing Pains
Released
October 16, 2007
Format
CD single, digital download
Recorded
2007
Genre
R&B
disco
funk
Length
4:02
Label
Geffen
Songwriter(s)
Mary J. Blige, Christopher Stewart, Terius Nash, Phalon Alexander
Producer(s)
Jazze Pha, Tricky Stewart, Kuk Harrell
Mary J. Blige singles chronology
"We Ride (I See the Future)"
(2006) "Just Fine"
(2007) "Work That"
(2007)
"We Ride (I See the Future)"
(2006) "Just Fine"
(2007) "Work That"
(2007)
"Just Fine" is a song by American recording artist Mary J. Blige. It was written by Blige along with producers Jazze Pha and Tricky Stewart for her eighth studio album, Growing Pains (2007), and released as the album's lead single in October 2007. A moderate commercial success, it peaked at number 22 on the US Billboard Hot 100 and number 16 on the UK Singles Chart, while also topping the Hot Dance Club Play chart. The track sold over 500,000 units in the United States alone and over 700,000 worldwide, making it eligible for gold status in the United States.
Critically acclaimed, "Just Fine" was nominated in the Best Female R&B Vocal Performance category at the 50th Annual Grammy Awards, held February 2008, as well as the Grammy for Best Remixed Recording, Non-Classical at the 51st Grammy Awards in February 2009. In addition, the song was ranked 41st on Rolling Stone's list of the 100 Best Songs of 2007.[1]
Contents
[hide]
1 Background
2 Remixes
3 Music video
4 Formats and track listings
5 Charts
5.1 Weekly charts
6 References
Background[edit]
Mary J. Blige said:
That song was written based on me having a good day. You know, I can have 20 bad days. I can have as many bad days as anyone. But I choose to say, 'I'm just fine.' Right now. So it's OK to have those days. So instead of coming with something ungrateful to the universe, how about I come with something first that's says, 'You know what? It's OK. Enjoy this day if you're having a great day.[2]
Remixes[edit]
The official remix was produced by Swizz Beatz called, "Just Fine (Treat 'Em Right Remix)", which sampled "Treat 'Em Right" by Chubb Rock and features Lil Wayne and Swizz Beatz on background vocals. There are four versions of this remix: The main remix version has Lil Wayne's verse on the beginning after the intro, the second remix version features a verse by Precise, along with Lil Wayne, the third remix version has Lil Wayne's verse on the near end of the song, and the fourth remix version is a no rap version, omitting Lil Wayne's verse.
The second official remix of "Just Fine" features Lil' Mama, which was a pre-order only track on iTunes when the album was released. An alternate music video for this remix was produced.
Music video[edit]
The music video for "Just Fine" was directed by Chris Applebaum and released on October 8, 2007. It premiered on BET and MTV's TRL on October 25, 2007. On September 7, 2008, the video was nominated for Best Hip-Hop Video at the 2008 MTV Video Music Awards. On December 20, 2008, VH1 ranked it 39th on its list for the "Top 40 of 2008".
Formats and track listings[edit]
UK CD promo
"Just Fine" (Main Version)
"Just Fine" (featuring Lil Mama)
"Just Fine" (Moto Blanco Radio Mix)
"Just Fine" (Moto Blanco Club Mix)
"Just Fine" (Moto Blanco Dub)
UK CD single
"Just Fine" (3:58)
"Just Fine" (Moto Blanco remix) (8:04)
International CD promo
"Just Fine" (Radio Edit) (3:58)
"Just Fine" (Main Version) (4:18)
"Just Fine" (Instrumental) (4:18)
Charts[edit]
Weekly charts[edit]
Chart (2007-2008)
Peak
position
Canada (Canadian Hot 100)[3] 84
Scotland (Official Charts Company)[4] 21
UK Singles (Official Charts Company)[5] 16
UK R&B (Official Charts Company)[6] 2
US Billboard Hot 100[7] 22
US Hot R&B/Hip-Hop Songs (Billboard)[8] 3
US Dance Club Songs (Billboard)[9] 1
References[edit]
Jump up ^ Rolling Stone Magazine The 100 Best Songs Of 2007 Popcrunch. Retrieved September 18, 2013
Jump up ^ Rodriguez, Jayson; Hernandez, Liz (October 23, 2007). "Mary J. Blige Says She's 'Just Fine' With Her New Album, Losing 'Umbrella' To Rihanna". MTV. Retrieved April 28, 2008.
Jump up ^ "Mary J. Blige – Chart history" Canadian Hot 100 for Mary J. Blige. Retrieved 2013-01-04.
Jump up ^ "Official Scottish Singles Sales Chart Top 100". Official Charts Company.
Jump up ^ "Mary J Blige: Artist Chart History". Official Charts Company. Retrieved 2013-01-03.
Jump up ^ "Official R&B Singles Chart Top 40". Official Charts Company.
Jump up ^ "Mary J. Blige – Chart history" Billboard Hot 100 for Mary J. Blige. Retrieved 2013-01-04.
Jump up ^ "Mary J. Blige – Chart history" Billboard Hot R&B/Hip-Hop Songs for Mary J. Blige. Retrieved 2013-01-04.
Jump up ^ "Mary J. Blige – Chart history" Billboard Hot Dance Club Songs for Mary J. Blige. Retrieved 2013-01-04.
Preceded by
"Love like This" by Natasha Bedingfield featuring Sean Kingston Billboard Hot Dance Club Play number-one single
February 16, 2008 Succeeded by
"GIve It All You Got" by Ultra Naté featuring Chris Willis
[hide]
v
t
e
Mary J. Blige singles
Discography
What's the 411?
"You Remind Me"
"Real Love"
"Reminisce"
"Sweet Thing"
"Love No Limit"
"You Don't Have to Worry"
"My Love"
My Life
"Be Happy"
"Mary Jane (All Night Long)"
" I'm Goin' Down"
"You Bring Me Joy"
"I Love You"
Share My World
"Love Is All We Need"
"I Can Love You"
"Everything"
"Missing You"
"Seven Days"
Mary
"As"
"All That I Can Say"
"Deep Inside"
"Your Child"
"Give Me You"
No More Drama
"Family Affair"
"Dance for Me"
"No More Drama"
"Rainy Dayz"
Love & Life
"Love @ 1st Sight"
"Ooh!"
"Not Today"
"Whenever I Say Your Name"
"It's a Wrap"
The Breakthrough
"MJB da MVP"
"Be Without You"
"One"
"Enough Cryin"
"Take Me As I Am"
Reflections (A Retrospective)
"We Ride (I See the Future)"
Growing Pains
"Just Fine"
"Work That"
"Stay Down"
Stronger with Each Tear
"The One"
"I Am"
"Each Tear"
"We Got Hood Love"
My Life II... The Journey Continues (Act 1)
"Ain't Nobody"
"25/8"
"Don't Mind"
"Mr. Wrong"
"Why"
"Love a Woman"
"Someone to Love Me (Naked)"
A Mary Christmas
"Do You Hear What I Hear?"
"This Christmas"
Think Like a Man Too
"Suitcase"
The London Sessions
"Doubt"
"Right Now"
"Therapy "
"Whole Damn Year"
Strength of a Woman
"Thick of It"
"U + Me (Love Lesson)"
"Love Yourself"
Soundtracks
"(You Make Me Feel Like) A Natural Woman"
"Not Gon' Cry"
"Stronger"
"The Living Proof"
Guest appearances
"911"
"Ain't No Way"
"America's Song"
"Bridge over Troubled Water"
"Can't Knock the Hustle"
"Disrespectful"
"F for You"
"Hands"
"I'll Be There for You/You're All I Need to Get By"
"I'm a Hustla (Remix)"
"IfULeave"
"Just Stand Up!"
"Lean on Me"
"Magic Touch (NYC Remix)"
"Now or Never"
"Remember Me"
"Runaway Love"
"Stay with Me (Remix)"
"Touch It (Remix)"
"Wake Up Call (Mark Ronson Remix)"
"What Child Is This"
"Where Is the Love?"
Book
Category
Retrieved from "https://en.wikipedia.org/w/index.php?title=Just_Fine&oldid=798082574"
Categories:
2007 singles
Mary J. Blige songs
Music videos directed by Chris Applebaum
Billboard Dance Club Songs number-one singles
Songs written by Mary J. Blige
Songs written by The-Dream
Songs written by Tricky Stewart
Song recordings produced by Tricky Stewart
Song recordings produced by Kuk Harrell
Song recordings produced by Jazze Pha
Songs written by Jazze Pha
2007 songs
Geffen Records singles
Funk songs
Hidden categories:
Use mdy dates from June 2013
Articles with hAudio microformats
Singlechart usages for Billboardcanadianhot100
Singlechart usages for Scotland
Singlechart usages for UKchartstats
Singlechart usages for UKrandb
Singlechart usages for Billboardhot100
Singlechart usages for Billboardrandbhiphop
Singlechart usages for Billboarddanceclubplay
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