Masking
Masks a sequence by using a mask value to skip timesteps.
Inherits From: Layer
tf.compat.v1.keras.layers.Masking
tf.compat.v2.keras.layers.Masking
For each timestep in the input tensor (dimension #1 in the tensor),
if all values in the input tensor at that timestep
are equal to mask_value
, then the timestep will be masked (skipped)
in all downstream layers (as long as they support masking).
If any downstream layer does not support masking yet receives such an input mask, an exception will be raised.
Consider a Numpy data array x
of shape (samples, timesteps, features)
,
to be fed to an LSTM layer.
You want to mask timestep #3 and #5 because you lack data for
these timesteps. You can:
x[:, 3, :] = 0.
and x[:, 5, :] = 0.
Masking
layer with mask_value=0.
before the LSTM layer:model = Sequential() model.add(Masking(mask_value=0., input_shape=(timesteps, features))) model.add(LSTM(32))
__init__
__init__( mask_value=0.0, **kwargs )


Application
class Application
extends
Component
Represents the application itself, encapsulates activities (AppActivity
components) and contexts for rendering and activation using URL-like paths.
Use the static run
method to create and activate an application using a set of activity constructors, or create an application class that includes activities as (preset) bound components.
Note: Do not use the Application
class directly, as it will not initialize rendering or activation contexts. Instead, use platform specific application classes such as BrowserApplication
that is exported by the @typescene/webapp
package.
Constructor
(): Application
.run() static
<T extends Application>(this: typeof Application, ...activities:
ComponentConstructor
<
AppActivity
>[]): T
Create an application that includes given activities, and start it immediately. If none of the activities has a path
property, then all activities are activated immediately; otherwise each activity will activate itself using the current activationContect
.
Returns: the application instance.
Note: Calling this method directly on Application
creates an application without any context (i.e. activationContext
and renderContext
). Instead, use a constructor that is meant for a specific platform (e.g. BrowserApplication
).
.active static
ManagedList
<Application>
All Application
instances that are currently active.
.setAutoUpdateHandler() static
<T extends ComponentConstructor<
Component
>>(f: (module: any, C: T, methodName: string & keyof T) => void): void
Set a handler that is used to register classes and modules for automatic update/reload; this method is used by e.g. @typescene/webapp
to support Hot Module Reload.
.registerAutoUpdate() static
<T extends ComponentConstructor<
Component
>>(module: any, C: T, methodName: string & keyof T): void
Register given class and module for automatic update/reload; this method is used by e.g. ViewActivity
and should not be used on its own.
.name
string
The application name.
.activities
List of root activities, as child components.
.renderContext
Application render context as a managed child object, propagated to all (nested) AppComponent
instances. This object is set by specialized application classes such as BrowserApplication
to match the capabilities of the runtime platform.
.activationContext
Activity activation context as a managed child object, propagated to all (nested) AppComponent
instances. This object is set by specialized application classes such as BrowserApplication
to match the capabilities of the runtime platform.
.activate()
(): this
Activate this application asynchronously, immediately creating all primary activities; any errors during activation are handled by logging them to the console (uses UnhandledErrorEmitter
).
Returns: the application itself.
.activateAsync()
(): Promise<void>
Activate this application, immediately creating all primary activities.
.deactivateAsync()
(): Promise<void>
Deactivate this application, immediately destroying all actvities.
.destroyAsync()
(): Promise<void>
Destroy this application, immediately destroying all activities.
.navigate()
(path: string): this
Navigate to given (relative) path using the current Application.activationContext
.
.goBack()
(): this
Go back to the previous navigation path, if implemented by the current Application.activationContext
.
.add()
(...activities:
AppActivity
[]): this
Add given activities to the application. Activities with matching paths will be activated immediately (see AppActivity.path
).
.showViewActivityAsync()
<TViewActivity extends AppActivity & { render: Function; }>(viewActivity: TViewActivity): Promise<TViewActivity>
Add given view activity to the application, and activate it immediately regardless of AppActivity.path
; this causes corresponding views to be rendered if possible.
Returns: A promise that resolves to the view activity after it has been activated.
.findService()
(name: string):
ManagedService
Returns the currently registered service with given name, if any. This is an alias of ManagedService.find()
.
.isPresetComponent() protected
(): boolean
Inherited from Component.isPresetComponent
.
.delegateEvent() protected
(e:
ManagedEvent
, propertyName: string): boolean | void
Inherited from Component.delegateEvent
.
.getParentComponent()
<TParent extends Component = Component>(ParentClass?:
ComponentConstructor
<TParent>): TParent
Inherited from Component.getParentComponent
.
.getBoundParentComponent()
<TParent extends Component>(ParentClass?:
ComponentConstructor
<TParent>): TParent
Inherited from Component.getBoundParentComponent
.
.emitAction()
(name: string, inner?:
ManagedEvent
, context?:
ManagedObject
): void
Inherited from Component.emitAction
.
.propagateComponentEvent() deprecated
(name: string, inner?:
ManagedEvent
): void
Inherited from Component.propagateComponentEvent
.
.managedId
number
Inherited from ManagedObject.managedId
.
.managedState
Inherited from ManagedObject.managedState
.
.getReferenceCount() protected
(): number
Inherited from ManagedObject.getReferenceCount
.
.getManagedReferrers() protected
():
ManagedObject
[]
Inherited from ManagedObject.getManagedReferrers
.
.getManagedParent() protected
<TParent extends ManagedObject = ManagedObject>(ParentClass?:
ManagedObjectConstructor
<TParent>): TParent
Inherited from ManagedObject.getManagedParent
.
.emit()
<TEvent extends ManagedEvent = ManagedEvent, TConstructorArgs extends any[] = any[]>(e: string | TEvent | (new (...args: TConstructorArgs) => TEvent), ...constructorArgs: TConstructorArgs): this
Inherited from ManagedObject.emit
.
.emitChange()
(name?: string): void
Inherited from ManagedObject.emitChange
.
.propagateChildEvents() protected deprecated
(...types: ((new (...args: any[]) =>
ManagedEvent
) | ((e:
ManagedEvent
) => any))[]): this
Inherited from ManagedObject.propagateChildEvents
.
.activateManagedAsync() protected
(): Promise<any>
Inherited from ManagedObject.activateManagedAsync
.
.deactivateManagedAsync() protected
(): Promise<void>
Inherited from ManagedObject.deactivateManagedAsync
.
.destroyManagedAsync() protected
(): Promise<void>
Inherited from ManagedObject.destroyManagedAsync
.
.onManagedStateActivatingAsync() protected
(): Promise<void>
Inherited from ManagedObject.onManagedStateActivatingAsync
.
.onManagedStateActiveAsync() protected
(): Promise<void>
Inherited from ManagedObject.onManagedStateActiveAsync
.
.onManagedStateDeactivatingAsync() protected
(): Promise<void>
Inherited from ManagedObject.onManagedStateDeactivatingAsync
.
.onManagedStateInactiveAsync() protected
(): Promise<void>
Inherited from ManagedObject.onManagedStateInactiveAsync
.
.onManagedStateDestroyingAsync() protected
(): Promise<void>
Inherited from ManagedObject.onManagedStateDestroyingAsync
.
Application.Presets
Application presets type, for use with Component.with
.
.name
string
Human readable application name.
.renderContext
Platform dependent application render context.
.activationContext
Platform dependent activation context (router).


|
Standard Reference Data Program |
Data Gateway |
Chemistry WebBook |
Go To: Top, Constants of diatomic molecules, References, Notes / Error Report
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: J.E. Bartmess
| Quantity | Value | Units | Method | Reference | Comment |
|---|---|---|---|---|---|
| ΔrH° | 1489. ± 11. | kJ/mol | D-EA | Arnold, Bradforth, et al., 1991 | gas phase |
| ΔrH° | <1572. ± 9.6 | kJ/mol | G+TS | Schiff and Bohme, 1975 | gas phase; No reaction with acetylene |
| Quantity | Value | Units | Method | Reference | Comment |
| ΔrG° | 1459. ± 12. | kJ/mol | H-TS | Arnold, Bradforth, et al., 1991 | gas phase |
| ΔrG° | <1542. ± 8.4 | kJ/mol | IMRB | Schiff and Bohme, 1975 | gas phase; No reaction with acetylene |
Go To: Top, Gas phase ion energetics data, References, Notes / Error Report
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Data compiled by: K.P. Huber and G. Herzberg
| State | Te | ωe | ωexe | ωeye | Be | αe | γe | De | βe | re | Trans. | ν00 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| a 4Σu+ | (19448) | (1074) 1 | (25) | (1.135) 1 | (0.0035) | (1.573) | ||||||
| B 2Σu+ | 18390.88 | 1968.73 Z | 14.433 | -0.324 | 1.87745 2 | 0.01776 | -0.00037 | 0.00000684 3 | 1.22330 | B ↔ X 4 V | 18483.98 Z | |
| missing citation | ||||||||||||
| A 2Πu 5 | A ← X | |||||||||||
| Lineberger and Patterson, 1972 | ||||||||||||
| X 2Σg+ | 0 | 1781.04 Z | 11.585 | -0.027 | 1.74685 | 0.0167 | 0.00000669 | 1.26821 |
| 1 | Constants derived Bondybey and Brus, 1975 from the perturbations Herzberg and Lagerqvist, 1968 in B 2Σu+. Ab initio calculations by Barsuhn, 1974 and Thulstrup and Thulstrup, 1974 independently predict the existence of a 4Σu+ state slightly above B 2Σu+ with re and ωe values near those derived from the perturbations. |
| 2 | Small perturbations by a 4Σu+. |
| 3 | Dv= +[1.0(v+1/2) + 0.08(v+1.2)2]E-7. |
| 4 | The spectrum was observed in flash discharges in CH4 Herzberg and Lagerqvist, 1968, behind reflected shock waves [fel ~ 0.017 Cathro and Mackie, 1973], and in rare gas matrices Milligan and Jacox, 1969, Frosch, 1971, Bondybey and Nibler, 1972, missing citation, Brus and Bondybey, 1975. Conclusive proof that it belongs to C2- was supplied by two-photon photodetachment spectroscopy Lineberger and Patterson, 1972. Franck-Condon factors Singh and Maheshwari, 1971. |
| 5 | Fragments of absorption bands. |
| 6 | From D00(C2) and the electron affinities of C2 and of C(=1.268 eV). |
| 7 | Photodetachment threshold Feldman, 1970. |
Go To: Top, Gas phase ion energetics data, Constants of diatomic molecules, Notes / Error Report
Data compilation copyright by the U.S. Secretary of Commerce on behalf of the U.S.A. All rights reserved.
Arnold, Bradforth, et al., 1991
Arnold, D.W.; Bradforth, S.E.; Kitsopoulos, T.N.; Neumark, D.M.,
Vibrationally Resolved Spectra of C2-C11 by Anion Photoelectron Spectroscopy,
J. Chem. Phys., 1991, 95, 8753. [all data]
Schiff and Bohme, 1975
Schiff, H.I.; Bohme, D.K.,
Flowing afterglow studies at York University,
Int. J. Mass Spectrom. Ion Phys., 1975, 16, 167. [all data]
Lineberger and Patterson, 1972
Lineberger, W.C.; Patterson, T.A.,
Two photon photodetachment spectroscopy: the C2--2Σ states,
Chem. Phys. Lett., 1972, 13, 40. [all data]
Bondybey and Brus, 1975
Bondybey, V.E.; Brus, L.E.,
Photophysics of C2-(B2Σu+) in rare gas lattices: vibrational relaxation through intermediate a4Σu+ levels,
J. Chem. Phys., 1975, 63, 2223. [all data]
Herzberg and Lagerqvist, 1968
Herzberg, G.; Lagerqvist, A.,
A new spectrum associated with diatomic carbon,
Can. J. Phys., 1968, 46, 2363. [all data]
Barsuhn, 1974
Barsuhn, J.,
Nonempirical calculations on the electronic spectrum of the molecular ion C2-,
J. Phys. B:, 1974, 7, 155. [all data]
Thulstrup and Thulstrup, 1974
Thulstrup, P.W.; Thulstrup, E.W.,
A theoretical investigation of the low-lying states of the C2- ion,
Chem. Phys. Lett., 1974, 26, 144. [all data]
Cathro and Mackie, 1973
Cathro, W.S.; Mackie, J.C.,
Oscillator strength of the C2-B2Σ - X2Σ transition: a shock-tube determination,
J. Chem. Soc. Faraday Trans. 2, 1973, 69, 237. [all data]
Milligan and Jacox, 1969
Milligan, D.E.; Jacox, M.E.,
Studies of the photoproduction of electrons in inert solid matrices. The electronic spectrum of the species C2-,
J. Chem. Phys., 1969, 51, 1952. [all data]
Frosch, 1971
Frosch, R.P.,
C2 and C2- spectra produced by the X irradiation of acetylene in rare-gas matrices,
J. Chem. Phys., 1971, 54, 2660. [all data]
Bondybey and Nibler, 1972
Bondybey, V.; Nibler, J.W.,
Laser excited fluorescence studies of matrix isolated C2-,
J. Chem. Phys., 1972, 56, 4719. [all data]
Brus and Bondybey, 1975
Brus, L.E.; Bondybey, V.E.,
Molecular ions and electron transport in rare gas lattices: C2- formation mechanism and X2Σg+ = B2Σu+ spectroscopy,
J. Chem. Phys., 1975, 63, 3123. [all data]
Singh and Maheshwari, 1971
Singh, I.D.; Maheshwari, R.C.,
Isotope/effect on Franck-Condon factors & r-centroids for the new (1Σu+-1Σg+) system of isotopic C2 molecule,
Indian J. Pure Appl. Phys., 1971, 9, 296. [all data]
Feldman, 1970
Feldman, D.,
Photoablosung von Elektronen bei einigen Stabilen Negativen Ionen,
Z. Naturfor., 1970, 25A, 621. [all data]
Go To: Top, Gas phase ion energetics data, Constants of diatomic molecules, References
| ΔrG° | Free energy of reaction at standard conditions |
| ΔrH° | Enthalpy of reaction at standard conditions |
Copyright for NIST Standard Reference Data is governed by the Standard Reference Data Act.
|
Standard Reference Data Program |
Data Gateway |
Chemistry WebBook |
If you have comments or questions about this site, please contact us.


20
Three well-known data sets are used by researchers in the universal lossles= s data compression field. The first one, the Calgary corpus, was introduced in 1989 by Bell e= t al. . The files in the corpus were chosen to cover up the typical types of data u= sed in computer processing. This corpus is rather old, and it contains some types of data which went ou= t of use, but the corpus is still a good benchmark used by many authors. The corpora proposed later, the Canterbury corpus and the large Canterbury corpus, contain files of similar sizes, less than 5 MB.
Over the years of using of these corpora some observations have proven thei= r important disadvantages. The most important in our opinion are:
The intention of the Silesia corpus is to provide a data set of files that covers the typical data types used nowadays. The sizes of the files are between 6 MB and 51 MB.
The chosen files are of different types and come from several sources. In our opinion, nowadays the two fastest growing types of data are multimed= ia and databases. The former are typically compressed with lossy methods so we do not include= them in the corpus. The database files, osdb, sao, nci, come from three different fields. The first one is a sample database from an open source project that is inte= nded to be used as a standard, free database benchmark. The second one, sao, is one of the astronomical star catalogues. This is a binary database composed of records of complex structure. The last one, nci, is a part of the chemical database of structures.
The sizes of computer programs are also growing rapidly. The standard corpora include only single, small routines, both in source an= d object code. Today it is almost impractical to compress every single source code file se= parately. The projects are composed of hundreds or thousands files, so it is a common= habit to compress it all together. We often can achieve a better compression ratio if we compress a concatenat= ed file of similar contents than the small separate ones. This trend is reflected in including a samba file. Besides the source codes, there is also a need to store the executables. We decided to include two files: ooffice and mozilla. The first one is a single medium-sized executable for the Windows system. The second is a concatenation of the whole application for Tru64 Unix system composed of executables, archives, texts, HTML files, and other.
There are also types of images that cannot be compressed loosely=E2=80=94the medical images. The sizes of such files are also huge and we include two examples of them i= n the corpus. The first file, x-ray, is an X-ray picture of a child's hand. The second file, mr, is a magnetic resonance, three dimensional image of a head.
The standard corpora contain text files. Moreover, these files are typically the largest files of them, but in our o= pinion there is a need to test the compression efficiency also on the larger ones stored in different file types. We propose three such files. The first, dickens, is a collection of some works by Charles Dickens that c= an be found in the Project Gutenberg. This is a plain text file. The second one, reymont, is a book Ch=EF=BF=BDopi by W=EF=BF=BDadys= EF=BF=BDaw Reymont stored in a PDF file. The PDF files can be internally-compressed but the quality of this build-in= compression is rather poor, and much better results can be obtained when we compress an uncompressed PD= F file. Because of this we enclose the uncompressed version. The last text file, webster, is an electronic version of The 1913 Webste= r Unabridged Dictionary taken from the Project Gutenberg. The file is stored in the HTML format. The last file of the new corpus, xml, is a concatenation of 21 XML fil= es. The XML standard is designed to be a universal file format for storing docu= ments, so we decided to enclose it.
| Filename | Description | Type | Source | Raw size [B] | Bzipped size [B] |
| dickens | Collected works of Charles Dickens | English text | Project Gutenberg | 10,192,446 | 2,799,528 |
| mozilla | Tarred executables of Mozilla 1.0 (Tru64 UNIX ed= ition) | exe | Mozilla Project | 51,220,480 | 17,914,392 |
| mr | Medical magnetic resonanse image | picture | Hospital image | 9,970,564 | 2,441,280 |
| nci | Chemical database of structures | database | CACTVS Chemical Information Services at LMC/NCI | 33,553,445 | 1,812,734 |
| ooffice | A dll from Open Office.org 1.01 | exe | Open Office | 6,152,192 | 2,862,526 |
| osdb | Sample database in MySQL format from Open Source= Database Benchmark | database | Open Source Database Benchmark Project | 10,085,684 | 2,802,792 |
| reymont | Text of the book Ch=EF=BF=BDopi by W=EF=BF=BDady= s=EF=BF=BDaw Reymont | Polish pdf | Virtual Library of Polish Literature | 6,627,202 | 1,246,230 |
| samba | Tarred source code of Samba 2-2.3 | src | Samba Project | 21,606,400 | 4,549,790 |
| sao | The SAO star catalog | bin data | Astronomical Catalogs and Catalog Format= s | 7,251,944 | 4,940,524 |
| webster | The 1913 Webster Unabridged Dictionary | html | Project Gutenberg | 41,458,703 | 8,644,714 |
| xml | Collected XML files | html | XMLPPM: XML-Conscious PPM Compress= ion | 5,345,280 | 441,186 |
| x-ray | X-ray medical picture | Hospital image | 8,474,240 | 4,051,112 | |
| Total | 211,938,580 | 54,506,808 |
Charles Dickens wrote many novels. The file is a concatenation of some, fou= rteen, of his works that can be found in the Project Gutenberg (A Child's History Of England, All The Year Round: Contributions, American Notes, The Battle Of Life, Bleak House, A Christmas Carol, David Copperfield, Dombey And Son, Doctor Marigold, Going Into Society, George Silverman's Explanation, Barnaby Rudge: a tale of the Riots of 'eighty, The Chimes, The Cricket On The Hearth). The file is a simple text.
MD5:<PHONE_NUMBER>9f6db57d79096bc0aca07e
A Mozilla 1.0 open source web browser was installed on the Tru64 UNIX opera= ting system and then the contents of the Mozilla.org directory were tarred. There are 525 files of such types as: executables, jar archives, HTML, XML, text, and others.
MD5: c7789a2097f1ff944b0c737430a339b3
A magnetic resonanse medical picture of a head. This file is stored is DICO= M format and contains 19 planes.
MD5: 38e623e3093b7bf2003ca4b1bbc19927
The chemical databases of strucures contain information of structures, thei= r components, 2D and/or 3D coordinates, properites, etc. The file is a part of the Aug= ust 2000 2D File stored in an SDF format which is common file format developped to handle a list of molecular structures associated with properties. The original database is of size 982MB so we had to truncate it to be suita= ble for a part of the corpus. The 32MB piece (rounded down to the nearest end of the record), we have chosen, is taken from the middle of the original file (starting at the first record after leaving 400MB of data).
MD5: 31f85bc8706f3c921104e7c169e2e2e1
An Open Office is an open source project, which is composed of the word pro= cessor, spreadsheet program, presentation maker, and graphical program. The file is a dynamic linked linbrary from version 1.01.
MD5: 573c4ae915e36631d8f2dcffb9b9b66d
An Open Source Database Benchmark is a project invented to provide a free t= est for database systems. One of the parts of the project are sample databases. The 40MB benchmark was run on the MySQL 3.23 server. The file is one of the MySQL database files, hundred.med.
MD5: e734b0c48e6a982adfb5802da3032ecd
A book Ch=EF=BF=BDopi by W=EF=BF=BDadys=EF=BF=BDaw Reymont was honou= red the Nobel Price in 1924. The text of the book was taken from the Virtual Library of Polish Literatur= e. Then it was converted to the LaTeX files from which the uncompressed PDF file was p= roduced. The file is uncompressed due to the fact the built-in compression in PDF fo= rmat is rather poor, and much better results can be obtained when we compress the uncompressed P= DF files.
MD5: d8f54d78105079775f32d76dc55fc671
Samba is an open souce project that is intended to be a free alternative to= the SMB/CIFS clients. The file contains tarred source code (also documentation, graphics) of the Samba 2.2-3 version.
MD5: 154eaea7ea70e89f6339ff0abf4112ca
There are many star catalogs containing the data of sky objects. The chosen= one, SAO catalog, is suitable especially for the amator astronomers. It contains the informat= ion about 258,996 stars, and is composed of binary records.
MD5: 79e95a22e18cd82b7e42bf91b380d30b
The 1913 Webster Unabridged Dictionary is an English dictionary stored in a= rather simple HTML. The file is a concatenation of files that can be obtained from Project Gute= nberg.
MD5: 474931ad907ac27bf962c75ded46c069
The XML is an incomming standard of document format. The importance of XML is still growing. The file is a corpus prepared for XMLPPM: XML-Conscious PPM Compression. Th= is is a concatenation of all, eleven, files.
MD5: 9b09c0c80104adb8aae910b7d7db003e
An X-ray medical picture of child's hand. This is a 12-bit gray scaled imag= e.
MD5: 9baec32ad14ec3eff487d254382cb91c
09


"""Tasks related to moving data in or out of Tamr using delimited files"""
from typing import Optional, List, Union
from functools import partial
from pathlib import Path
import csv
import logging
import os
import requests
from tamr_unify_client.dataset.resource import Dataset
from tamr_unify_client.project.resource import Project
from tamr_toolbox.utils import operation
from tamr_toolbox.data_io import common
LOGGER = logging.getLogger(__name__)
[docs]def from_dataset(
dataset: Dataset,
export_file_path: Union[Path, str],
*,
csv_delimiter: str = ",",
columns: Optional[List[str]] = None,
flatten_delimiter: str = "|",
quote_character: str = '"',
quoting: int = csv.QUOTE_MINIMAL,
na_value: str = "NaN",
nrows: Optional[int] = None,
allow_dataset_refresh: bool = False,
buffer_size: int = 10000,
overwrite: bool = False,
) -> int:
"""
Export a Tamr Dataset to a csv file. Records are streamed to disk and written according to a
given buffer size. As a result this is more memory efficient than first reading to a
pandas.DataFrame and writing to CSV.
Args:
dataset: Tamr Dataset object
export_file_path: Path to the csv file where the dataset will be saved
csv_delimiter: Delimiter of the csv file
columns: Optional, Ordered list of columns to write. If None, write all columns in
arbitrary order.
flatten_delimiter: Flatten list types to strings by concatenating with this delimiter
quote_character: Character used to escape value for csv delimiter when it appears in the
value.
quoting: The escape strategy to use according to the Python csv writer.
See https://docs.python.org/2/library/csv.html#csv.QUOTE_MINIMAL
na_value: Value to write that represents empty or missing data.
See https://pandas.pydata.org/pandas-docs/stable/reference/api/pandas.read_csv.html
for the na_values supported by default in pandas.read_csv
nrows: Optional, Number of rows to write. If None, then write all rows.
allow_dataset_refresh: If True, allows running a job to refresh dataset to make streamable.
Otherwise a RuntimeError will be thrown if the dataset is unstreamable.
buffer_size: Number of records to store in memory before writing to disk
overwrite: if True and export_file_name already exists, overwrite the file.
Otherwise throw an error
Returns:
The total number of records written
Raises:
FileExistsError: if the csv file to which the dataset is to be streamed exists
and `overwrite` is False
RuntimeError: if `dataset` is not streamable and `allow_dataset_refresh` is False
ValueError: if `columns` or `flatten_columns` contain columns that are not
present in `dataset`
"""
LOGGER.info(
f"Streaming records to csv file {export_file_path} from dataset {dataset.name} "
f"(id={dataset.resource_id})."
)
if os.path.exists(export_file_path):
if not overwrite:
message = (
f"CSV file {export_file_path} already exists. "
f"(Set 'overwrite' flag to True if you wish to overwrite)"
)
LOGGER.error(message)
raise FileExistsError(message)
else:
LOGGER.warning(f"CSV file {export_file_path} already exists and will be overwritten")
if csv_delimiter == flatten_delimiter:
message = (
f"The CSV delimiter '{csv_delimiter}' cannot be identical to the list "
f"flattening delimiter '{flatten_delimiter}'"
)
LOGGER.error(message)
raise ValueError(message)
attribute_names = [attr.name for attr in dataset.attributes]
# check that specified columns exist
if columns is not None:
common._check_columns_subset(
input_list=columns, reference_list=attribute_names, raise_error=True
)
if not dataset.status().is_streamable:
if allow_dataset_refresh:
LOGGER.info(f"Refreshing dataset {dataset.name} to make streamable.")
op = dataset.refresh()
operation.enforce_success(op)
else:
message = (
f"Dataset {dataset.name} is not streamable. Refresh it first, or "
f"run with allow_dataset_refresh=True"
)
LOGGER.error(message)
raise RuntimeError(message)
func = partial(common._flatten_list, delimiter=flatten_delimiter, force=True)
# Open CSV file and use newline='' as recommended by
# https://docs.python.org/3/library/csv.html#csv.writer
with open(export_file_path, "w", newline="") as csv_file:
csv_writer = csv.writer(
csv_file, delimiter=csv_delimiter, quotechar=quote_character, quoting=quoting,
)
buffer = []
header = None
# Set record number to -1 in case the dataset streamed has no records
record_number = -1
for record_number, record in enumerate(
common._yield_records(dataset, func=func, columns=columns)
):
# Obtain and write the header information only on the first pass
if header is None:
header = record.keys() if columns is None else columns
csv_writer.writerow(header)
# Replace empty values with a specific null value
# This also allows nulls to be treated differently from empty strings
record = [na_value if record[k] is None else record[k] for k in header]
buffer.append(record)
at_max_buffer = buffer_size is not None and (len(buffer) >= buffer_size)
at_max_rows = nrows is not None and record_number >= nrows - 1
if at_max_buffer or at_max_rows:
csv_writer.writerows(buffer)
LOGGER.debug(f"Written dataset {dataset.name} up to record {record_number+1}")
buffer = []
if at_max_rows:
break
# Write anything remaining
# This will occur whenever the buffer is non-zero and the number of records
# is not exactly divisible by the buffer number
# For example, writing a dataset with 1100 records using a buffer size of 500
# will write in 3 chunks: 2 x 500 above and the remaining 100 handled here
if len(buffer) != 0:
LOGGER.debug(f"Written dataset {dataset.name} up to record {record_number + 1}")
csv_writer.writerows(buffer)
if record_number == -1:
# If record number is -1 then no records were streamed, possibly because the dataset
# has no records. We therefore want to simply save the headers
if columns is not None:
csv_writer.writerow(columns)
else:
csv_writer.writerow(attribute_names)
records_written = record_number + 1
LOGGER.info(
f"Wrote {records_written} from dataset {dataset.name} (id={dataset.resource_id}) "
f"to {export_file_path}"
)
return records_written
[docs]def from_taxonomy(
project: Project,
export_file_path: Union[Path, str],
*,
csv_delimiter: str = ",",
flatten_delimiter: str = "|",
quote_character: str = '"',
quoting: int = csv.QUOTE_MINIMAL,
overwrite: bool = False,
) -> int:
"""
Export a Tamr taxonomy to a csv file. Records are streamed to disk and written according to a
given buffer size.
Args:
project: Tamr Project object
export_file_path: Path to the csv file where the dataset will be saved
csv_delimiter: Delimiter of the csv file
flatten_delimiter: Flatten list types to strings by concatenating with this delimiter
quote_character: Character used to escape value for csv delimiter when it appears in the
value.
quoting: The escape strategy to use according to the Python csv writer.
See https://docs.python.org/2/library/csv.html#csv.QUOTE_MINIMAL
overwrite: if True and export_file_name already exists, overwrite the file.
Otherwise throw an error
Returns:
The total number of records written
Raises:
FileExistsError: if `export_file_path` exists and `overwrite` is set to False
IOError: if the specified filepath does not exist or cannot be accessed
RuntimeError: if the classification project is not yet associated with a taxonomy or
taxonomy cannot be written to a csv file
TypeError: if the project type is not classification
ValueError: if `columns` and `flatten_columns` are identical values
"""
LOGGER.info(
f"Streaming taxonomy to csv file {export_file_path} from project {project.name} "
f"(project id={project.resource_id})."
)
try:
project = project.as_categorization()
except TypeError:
not_categorization_error = f"Project {project.name} is not a classification project."
LOGGER.error(not_categorization_error)
raise TypeError(not_categorization_error)
if os.path.exists(export_file_path):
if not overwrite:
message = (
f"CSV file {export_file_path} already exists. "
f"(Set 'overwrite' flag to True if you wish to overwrite)"
)
LOGGER.error(message)
raise FileExistsError(message)
else:
LOGGER.warning(f"CSV file {export_file_path} already exists and will be overwritten")
if csv_delimiter == flatten_delimiter:
message = (
f"The CSV delimiter '{csv_delimiter}' cannot be identical to the list "
f"flattening delimiter '{flatten_delimiter}'"
)
LOGGER.error(message)
raise ValueError(message)
try:
taxonomy = project.as_categorization().taxonomy()
except requests.exceptions.RequestException:
no_taxonomy_error = f"Project {project.name} is not associated with any taxonomy yet."
LOGGER.error(no_taxonomy_error)
raise RuntimeError(no_taxonomy_error)
# obtain categories and store in a list
categories = taxonomy.categories()
taxonomy_list = []
for category in categories:
taxonomy_list.append(category.path)
# sort the categories
taxonomy_list.sort()
# Open CSV file and use newline='' as recommended by
# https://docs.python.org/3/library/csv.html#csv.writer
try:
f = open(export_file_path, "w", newline="", encoding="utf-8")
except (FileNotFoundError, IOError, PermissionError):
cannot_open_error = f"File path {export_file_path} could not be opened for writing."
LOGGER.error(cannot_open_error)
raise IOError(cannot_open_error)
else:
try:
csv_writer = csv.writer(
f, delimiter=csv_delimiter, quotechar=quote_character, quoting=quoting,
)
csv_writer.writerows(taxonomy_list)
except csv.Error as e:
general_error = (
"Encountered an error while writing taxonomy categories to "
f"{export_file_path}: {e}"
)
f.close()
LOGGER.error(general_error)
raise RuntimeError(general_error)
finally:
f.close()
records_written = len(taxonomy_list)
LOGGER.info(
f"Wrote {records_written} categories from {project.name} taxonomy (project id"
f"={project.resource_id}) to {export_file_path}"
)
return records_written


Administration
The Administration shall consist of: Chief Executive Officer (CEO), Treasurer, Secretary/Administrative Assistant, and any other officers appointed by the Shura.
The Administration team will:- Conduct the affairs of the IAR within the policies and guidelines of the Shura.
- Implement decisions of the Shura.
- Appoint, coordinate and supervise activities of different committees.
- Allocate budgeted funds for various committees, activities and project(s) approved by the Shura.
- Act as liaison between LLCs and the Shura.
- Resolve conflict(s) related to member(s) and membership before referring it to Shura (see Article V, Sec 3).
The Administration Team
| Position | Name | Phone | |
| CEO | Hassan Imam |<PHONE_NUMBER> ext 1349 |<EMAIL_ADDRESS>|
| Treasurer | Abdirahman Roble |<EMAIL_ADDRESS>| |
| Facility Maintenance Chair | Wael Saleh |<PHONE_NUMBER> |<EMAIL_ADDRESS>|
IAR Committee Chairpersons
| Position | Name | Phone | |
| Al-Furqan School | Shahmeem Rajak |<PHONE_NUMBER> |<EMAIL_ADDRESS>|
| Al-Iman School | Firdos Pathan |<PHONE_NUMBER> |<EMAIL_ADDRESS>|
| An-Noor School | Farooq Cheema | farooq.cheema@ annoorquranacademy.org |
|
| Cemetery | Tahir Abualhawa |<PHONE_NUMBER> |<EMAIL_ADDRESS><EMAIL_ADDRESS>|
| Dawah Outreach |
Fiaz Fareed |<PHONE_NUMBER> |<EMAIL_ADDRESS>|
| Education | Yousef Badar |<PHONE_NUMBER> |<EMAIL_ADDRESS>|
| Finance | Mariya Shaikh |<PHONE_NUMBER> |<EMAIL_ADDRESS><EMAIL_ADDRESS>|
| Facility Maintenance | Wael Saleh |<PHONE_NUMBER> |<EMAIL_ADDRESS>|
| Planning & Construction | Imran Aukhil |<EMAIL_ADDRESS>| |
| Security & Safety | Rashid Salahat |<PHONE_NUMBER> |<EMAIL_ADDRESS><EMAIL_ADDRESS>|
| Older Adult Committee | Raqiia Abdul-Malik |<PHONE_NUMBER> |<EMAIL_ADDRESS><EMAIL_ADDRESS>|
| Social & Welfare | Mohamed Elgamal |<EMAIL_ADDRESS>| |
| Sports & Recreation | April Ackles |<PHONE_NUMBER> |<EMAIL_ADDRESS>|
| Media | Hassan Imam |<PHONE_NUMBER> ext 1349 |<EMAIL_ADDRESS>|
| Women | Alice Hines |<PHONE_NUMBER> ext 1342 |<EMAIL_ADDRESS>|
| Youth | Ahmed B. |<PHONE_NUMBER> ext 1334 |<EMAIL_ADDRESS>|
| Events | Mohammed |<EMAIL_ADDRESS>| |
| Fundraising | Osama Said |<PHONE_NUMBER> ext 1344 |<EMAIL_ADDRESS>|
| Membership | Aman Mohammed |<EMAIL_ADDRESS>| |
| Technology | Amjed Albataineh |<EMAIL_ADDRESS>| |
| IT / Web Site | Ameir Al-Zoubi |<EMAIL_ADDRESS>|


- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'left black lenticular bracket'.
|
|
first-letter-punctuation-389 |
= |
|
First-letter with the 'left tortoise shell bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'left tortoise shell bracket'.
|
|
first-letter-punctuation-390 |
= |
|
First-letter with the 'left white lenticular bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'left white lenticular bracket'.
|
|
first-letter-punctuation-391 |
= |
|
First-letter with the 'left white tortoise shell bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'left white tortoise shell bracket'.
|
|
first-letter-punctuation-392 |
= |
|
First-letter with the 'left white square bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'left white square bracket' .
|
|
first-letter-punctuation-393 |
= |
|
First-letter with the 'reversed double prime quotation mark' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'reversed double prime quotation mark'.
|
|
first-letter-punctuation-394 |
= |
|
First-letter with the 'ornate left parenthesis' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'ornate left parenthesis'.
|
|
first-letter-punctuation-395 |
= |
|
First-letter with the 'presentation form for vertical left white lenticular bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'presentation form for vertical left white lenticular bracket'.
|
|
first-letter-punctuation-396 |
= |
|
First-letter with the 'presentation form for vertical left parenthesis' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'presentation form for vertical left parenthesis'.
|
|
first-letter-punctuation-397 |
= |
|
First-letter with the 'presentation form for vertical left curly bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'presentation form for vertical left curly bracket'.
|
|
first-letter-punctuation-398 |
= |
|
First-letter with the 'presentation form for vertical left tortoise shell bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'presentation form for vertical left tortoise shell bracket'.
|
|
first-letter-punctuation-399 |
= |
|
First-letter with the 'presentation form for vertical left black lenticular bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'presentation form for vertical left black lenticular bracket'.
|
|
first-letter-punctuation-400 |
= |
|
First-letter with the 'presentation form for vertical left double angle bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'presentation form for vertical left double angle bracket'.
|
|
first-letter-punctuation-401 |
= |
|
First-letter with the 'presentation form for vertical left angle bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'presentation form for vertical left angle bracket'.
|
|
first-letter-punctuation-402 |
= |
|
First-letter with the 'presentation form for vertical left corner bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'presentation form for vertical left corner bracket'.
|
|
first-letter-punctuation-403 |
= |
|
First-letter with the 'presentation form for vertical left white corner bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'presentation form for vertical left white corner bracket'.
|
|
first-letter-punctuation-404 |
= |
|
First-letter with the 'presentation form for vertical left square bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'presentation form for vertical left square bracket'.
|
|
first-letter-punctuation-405 |
= |
|
First-letter with the 'small left parenthesis' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'small left parenthesis'.
|
|
first-letter-punctuation-406 |
= |
|
First-letter with the 'small left curly bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'small left curly bracket'.
|
|
first-letter-punctuation-407 |
= |
|
First-letter with the 'small left tortoise shell bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'small left tortoise shell bracket'.
|
|
first-letter-punctuation-408 |
= |
|
First-letter with the 'fullwidth left parenthesis' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'fullwidth left parenthesis'.
|
|
first-letter-punctuation-409 |
= |
|
First-letter with the 'fullwidth left square bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'fullwidth left square bracket'.
|
|
first-letter-punctuation-410 |
= |
|
First-letter with the 'fullwidth left curly bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'fullwidth left curly bracket'.
|
|
first-letter-punctuation-411 |
= |
|
First-letter with the 'fullwidth left white parenthesis' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'fullwidth left white parenthesis'.
|
|
first-letter-punctuation-412 |
= |
|
First-letter with the 'halfwidth left corner bracket' punctuation character
- Punctuation characters defined in Unicode [UNICODE] in (Ps),(Pe),(Pi),(Pf) and (Po) punctuation classes that precede or follow the first letter are included in first-letter selection - 'halfwidth left corner bracket'.
|
|
first-letter-quote-001 |
= |
|
:first-letter
|
|
first-letter-quote-002 |
= |
|
:first-letter
|
|
first-letter-quote-003 |
= |
|
:first-letter
|
|
first-letter-quote-004 |
= |
DOM/JS |
:first-letter
|
|
first-letter-quote-005 |
= |
|
:first-letter
|
|
first-letter-quote-006 |
= |
|
:first-letter
|
|
first-letter-selector-000 |
= |
|
:first-letter in XML
|
|
first-letter-selector-001 |
= |
|
First-letter pseudo-element
- The :first-letter pseudo-element matches the first letter in a given element.
|
|
first-letter-selector-002 |
= |
Bitmaps |
First-letter pseudo-element with image missing alt text
- If there is preceding content (an image) or alt text the :first-letter pseudo-element does not match the first letter.
|
|
first-letter-selector-003 |
= |
|
First-letter as a digit
- The ':first-letter' applies if the first letter is a digit.
|
|
first-letter-selector-004 |
= |
|
First-letter and :before
- If an element has ':before' or ':after' content, the ':first-letter applies to the first letter of the element including that content.
|
|
first-letter-selector-005 |
= |
|
First-letter with leading line break
- The first letter occurs on the first formatted line.
|
|
first-letter-selector-006 |
|
|
First-letter with list items
- If an element is a list item, the ':first-letter' applies to the first letter in the principal box after the marker.
|
|
first-letter-selector-007 |
= |
|
First-letter with table cell elements
- The :first-letter pseudo-element applies to table-cells.
|
|
first-letter-selector-008 |
= |
|
First-letter with inline-block elements
- The first-letter pseudo-element applies to inline-block elements.
|
|
first-letter-selector-009 |
|
|
First-letter and valid properties
- The color, font-size, text-decoration, text-transform, background and border properties apply to :first-letter.
|
|
first-letter-selector-010 |
|
|
First-letter as a float
- The float property applies to :first-letter.
|
|
first-letter-selector-011 |
|
|
First-letter using letter-spacing property
- The letter-spacing property is allowed for :first-letter.
|
|
first-letter-selector-012 |
|
|
First-letter using margin
- The margin property is allowed for :first-letter.
|
|
first-letter-selector-013 |
|
|
First-letter using background and padding
- The background and padding properties is allowed for :first-letter.
|
|
first-letter-selector-014 |
|
|
First-letter using vertical-align and line-height
- The vertical-align and line-height properties is allowed for :first-letter.
|
|
first-letter-selector-015 |
|
Bitmaps |
First-letter with img alt text
- The ':first-letter' pseudo-element can be used with all such elements that contain text, or that have a descendant in the same flow that contains text.
|
|
first-letter-selector-016 |
|
Bitmaps |
First-letter with img preceding text
- First-letter selects the first letter of a block if it is not preceded by any other content on its line.
|
|
first-letter-selector-018 |
|
|
First-letter with punctuation
- The ':first-letter' pseudo-element also applies to punctuation.
|
|
first-letter-selector-019 |
= |
|
First-letter in descendents
- A user agent acts as if the fictional start tag of the first-letter pseudo-element is just before the first text of the element, even if that first text is in a descendant.
|
|
first-letter-selector-020 |
|
Optional |
First-letter and language specific letter combinations
- Some letter combinations in some languages may be considered part of the first-letter pseudo-element.
|
|
first-letter-selector-021 |
|
Optional |
First-letter on list-style-position: inside
- User agents may ignore ':first-letter' on list items with 'list-style-position: inside'.
|
|
first-letter-selector-022 |
|
Optional |
First-letter in different elements than its punctuation
- If the letters that would form the first-letter are not in the same element the user agent may create a first-letter pseudo-element from one of the elements, both elements, or simply not create a pseudo-element.
|
|
first-letter-selector-023 |
|
Optional |
First-letter on bidi text
- If the first letter of the block is not at the start of the line (for example due to bidirectional reordering), then the user agent need not create the pseudo-element.
|
|
first-letter-selector-025 |
|
|
First-letter with table caption elements
- The :first-letter pseudo-element applies to table-captions.
|
|
first-letter-selector-026 |
|
|
First-Letter: Basic Test
|
|
first-letter-selector-027 |
|
|
First-Letter: Basic Test
|
|
first-letter-selector-028 |
= |
|
First-letter - in-flow block descendant that contains text
- The :first-letter pseudo-element can be used and will apply onto in-flow block descendant that contains text.
|
|
first-letter-selector-029 |
|
Interact |
First-letter - dynamic :hover pseudo-class
- The :first-letter pseudo-element can be used and will apply onto an :hover pseudo-class.
|
|
first-letter-space-not-selected |
= |
|
::first-letter - spaces should not be selected
- ::first-letter should not include initial spaces. Test non-breaking space, em space, en space, and thin space, both alone and preceeding a real letter.
|


You can fine-tune your client/server system with server load-balancing and client thread use of pool connections. For example, you can configure how often the servers check their load with the cache server load-poll-interval
property, or configure your own server load metrics by implementing the org.apache.geode.cache.server
package.
How Server Load Conditioning Works
When the client pool requests connection information from the server locator, the locator returns the least-loaded server for the connection type. The pool uses this “best server” response to open new connections and to condition (rebalance) its existing pool connections.
- The locator tracks server availability and load according to information that the servers provide. Each server probes its load metrics periodically and, when it detects a change, sends new information to the locator. This information consists of current load levels and estimates of how much load would be added for each additional connection. The locator compares the load information from its servers to determine which servers can best handle more connections.
- You can configure how often the servers check their load with the cache server’s
load-poll-interval
. You might want to set it lower if you find your server loads fluctuating too much during normal operation. The lower you set it, however, the more overhead your load balancing will use. - Between updates from the servers, the locators estimate which server is the least loaded by using the server estimates for the cost of additional connections. For example, if the current pool connection load for a server’s connections is 0.4 and each additional connection would add 0.1 to its load, the locator can estimate that adding two new pool connections will take the server’s pool connection load to 0.6.
- Locators do not share connection information among themselves. These estimates provide rough guidance to the individual locators for the periods between updates from the servers.
Geode provides a default utility that probes the server and its resource usage to give load information to the locators. The default probe returns the following load metrics:
- The pool connection load is the number of connections to the server divided by the server’s max-connections
setting. This means that servers with a lower max-connections
setting receives fewer connections than servers with a higher setting. The load is a number between 0 and 1, where 0 means there are no connections, and 1 means the server is at max-connections
. The load estimate for each additional pool connection is 1/max-connections
.
- The subscription connection load is the number of subscription queues hosted by this server. The load estimate for each additional subscription connection is 1.
To use your own server load metrics instead of the default, implement the ServerLoadProbe
or ServerLoadProbeAdapter
and related interfaces and classes in the org.apache.geode.cache.server
package. The load for each server is weighed relative to the loads reported by other servers in the system.
Client Thread Use of Pool Connections
By default, a client thread retrieves a connection from the open connection pool for each forwarded operation and returns the connection to the pool as soon as the request is complete. If your client thread runs a put
on a client region, for example, that operation grabs a server connection, sends the put
to the server, and then returns the connection to the pool. This action keeps the connections available to the most threads possible.
Set Up a Thread-Local (Dedicated) Connection
You configure threads to use dedicated connections by setting thread-local-connections
to true. In this case the thread holds its connection either until the thread explicitly releases the connection, or the connection expires based on idle-timeout
or load-conditioning-interval
.
Release a Thread-Local Connection
If you use thread-local connections, you should release the connection as soon as your thread finishes its server activities.
Call releaseThreadLocalConnection
on the Pool
instance you are using for the region:
Region myRegion ...
PoolManager.find(myRegion).releaseThreadLocalConnection();


bde: Bounded Density Estimation
A collection of S4 classes which implements different methods to estimate and deal with densities in bounded domains. That is, densities defined within the interval [lower.limit, upper.limit], where lower.limit and upper.limit are values that can be set by the user.
| Version: |
1.0.1 |
| Depends: |
R (≥ 2.0), shiny, ggplot2 |
| Imports: |
methods |
| Published: |
2015-02-16 |
| Author: |
Guzman Santafe, Borja Calvo, Aritz Perez and Jose A. Lozano |
| Maintainer: |
Guzman Santafe <guzman.santafe at unavarra.es> |
| License: |
GPL-2 |
| NeedsCompilation: |
no |
| Materials: |
NEWS |
| CRAN checks: |
bde results |
Downloads:
Reverse dependencies:
Linking:
Please use the canonical form
https://CRAN.R-project.org/package=bde
to link to this page.


very short list is becoming Observer / Short List. We’ll still deliver you the same delightful mix of cultural gems selected by a different curator each time—but with a new look and feel. We’ll also include some of the day’s best style, innovation and culture stories on Observer.com.
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a tiny game
i know a number between 1 - 100.
can you guess it?
Enter your guess here:
check it
reset game


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WITNESS LIST
Homeland Security & Public Safety Committee
May 1, 2013 - 8:00 AM
invited testimony from state resources regarding chemical facilities
On:
Albus, Gary (Texas department of public safety)
Conealy, Chris (State fire Marshal)
DeBerry, Drew (Texas Department of Agriculture)
Dendy, Kirby (Texas dept of public safety)
Henry, Hoyt (DSHS)
Herrman, Tim (Office texas state chemist)
Hoestenbach, Roger (Office of the Texas State Chemist)
Jones, Benjamin (Office texas state chemist)
Kidd, Nim (Texas Dept of Public Safety Division of Emergency Management)
Kistner, Kelly (State Fire Marshal)
Kitzman, Eleanor (Texas Department of Insurance)
Lakey, David (Department of State Health Services)
McCraw, Steven (DPS)
McCraw, Steven C. (Department of Public Safety)
Perkins, Kathy (Department of State of Health Services)
Shaw, Bryan (Tceq)
Registering, but not testifying:
On:
Goetz, Casey (Texas DPS)
Moreno, Rachael (State Fire Marshall)
1


--- layout: post title: "aiming" comments: true ---
The arrow impacted just above my sixth intercostal support, penetrating my secondary sub-processor. Fortunatly none of my bio-functions seem affected. Do not be concerned counselor, I believe your aim is improving.


Not sure if this can be done but some kind of Battlelog log file would be awesome, that keep all your chat history would be awesome.
Kinda like Xfire does but yeah that's a different thing.
Thanks
xXJumpyXx
Helping Hand
This sounds interesting.
I've found myself sometimes needing some link or something that someone sent me in the chat but the chat is cleared when I need it.
Prokill
Any info on this ?
ORFK
Global Moderator
No, currently we dont have any information if we will release this feature or not.
we and you will see it ;-)
BrainFooLong
Administrator
Complicated to implement - Will also blow the browsers storage quota away, maybe, if some user chat a lot. Chrome is very limited with storage and also have no real file access to disk (in the current bblog configuration).


Padmaavat
This fictional story is set in 13th century medieval India. a Princess of Sinhala(modern-day Sri Lanka) called Padmavati falls in love with an already married Maharawal Ratan Singh, King of Chittor. Upon their marriage, Padmavati is crowned queen, taking the place of the legal wife and queen consort of Ratan Singh and they reside together in joy and splendor. Their perfect life takes an unfortunate turn when a Court priest Chetan, banished by his king Ratan Singh, approaches Sultan of Delhi Allauddin Khilji and convinces him to attack Chittor and capture Padmavati for her beauty and absolute luck she brings to the king she marries.....
watch now


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WELCOME
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Picture by : Daggy J (Creative Commons Certified)
What Kind of Professional Group Would You Like to Create?
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About
Problem
Hygiene is a basic human necessity and a human right. Keeping public, as well as personal, hygiene up to standards is critical to maintain the health of a city or population. This requires a city like Seattle, which includes a large homeless population, to require enough public hygiene stations for those who need it. According to Seattle Magazine, a lack of 24-hour public restrooms downtown contributes to sanitation hazards and the spreading of diseases. As of January 1st 2019, Seattle had cut funding for hygiene centers downtown, leaving the homeless to relieve themselves wherever and whenever they can. As allocating funding and continuing the upkeep of public restrooms has previously failed in Seattle, city council members have made an effort to position restroom inaccessibility as a general public health issue, and not just one pertaining to our unsheltered population. Ballard has implemented one portable restroom, while the University District’s attempt is hindered by disagreeable maintenance fees. So, as Seattle slowly makes advances to attempt to fix this issue, we hope to help sheltered and unsheltered populations alike find alternatives close to where they are.
What we plan to do
The current map map above does not have the ability to zoom in and out, and lacks basic details. It is complex and does not have enough affordances to make it clear how it's supposed to be used. We also plan on adding a feature called "add a bathroom", that will allow users to add a bathroom to the current list.
Solution
We plan on focusing on this issue and creating a solution that will allow anyone to get access to the nearest restroom that is open to public, free or paid. At the moment, the city of Seattle has somewhat of an interactive map, but it is geared towards the homeless and lackluster in design and function. Our idea is to cater towards all citizens and create an interactive map that shows the locations of the nearest restrooms, laundry, showers, etc. including ones in restaurants and stores. After a certain period (TBD), we will ask the user to submit feedback on whether the restroom was accessible, free, clean, had a child station, etc. This information will be stored to improve the experience for people planning to use this tool in the future. Here is an image of what the map currently looks like:


The Weather App
Enter the name of your city
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© Kushagra Singh. All Rights Reserved.


WaitSystem()
This system process Entities with a WaitComponent. After the waitTime, that's specified in the WaitComponent, is elapsed, the WaitComponent is removed. The WaitComponent is used to delay the processing of other components through other systems.


Hong Kong Stocks Rally After Pro-Democracy Groups Dominate Polls
by Bloomberg(Bloomberg) -- Hong Kong stocks climbed after pro-democracy candidates swept the board in district council elections, putting pressure on the city’s government to address issues that have fueled months of protests.
The Hang Seng Index rose 1.5%. The gain was led by developers and other stocks seen as most sensitive to the demonstrations, which have weighed on the city’s stocks.
Wharf Real Estate Investment and New World Development Co. were among the top performers on Monday, while MTR Corp., which operates the city’s underground railway, rallied 2.6%. The MSCI Hong Kong Index gained 1.8%.
Pro-democracy candidates took at least 278 seats of the 452 up for grabs, according to the South China Morning Post, about seven times more than the pro-government camp. Pro-democracy groups gained control of at least 12 of the 18 district councils after failing to win a majority in any of them four years ago, the report said.


By @astronomyblog & @LoveGraphs. Stats last updated 4 January 2019.
It seems there may have been at least 54 shows and 368 listed appearances. With 7 people per show, Comedy.co.uk and Wikipedia are missing at least 3% of appearances (and probably a similar percent of people). The host/captains/regulars have included Greg Davies (Taskmaster × 54), Alex Horne (Assistant × 54).
Total appearances:
Guest appearances i.e. ignoring the host/captains/regulars:
All people:
Guests i.e. ignoring the host/captains/regulars:
Last updated: 2019/01/04


Next: 5 Example 4: Using
Up: 4 Examples
Previous: 3 Example 2: Control
Contents
Subsections
Note: Line numbers are not included in program but used just
for explanations !
1 -- This must be in first line
2 include c16f877
3
4
5
6
7 -- config fuses
8 pragma target protection off
9 pragma target debug off
10 pragma target cdp off
11 pragma target lvp off
12 pragma target bor off
13 pragma target powerup on
14 pragma target watchdog off
15 pragma target osc xt
16
17 -- Fosc definition
18 pragma target clock 4_000_000
19
20
21 -- PORTB and TRISB definitions
22 var volatile byte PORTB at {0x06,0x106}
23 var volatile byte TRISB at {0x86,0x186}
24
25 -- B0 pin definition
26 var volatile bit pin_b0 at PORTB : 0
27
28 -- B4 pin definition
29 var volatile bit pin_b4 at PORTB : 4
30
31
32 -- Button at pin_b0
33 var volatile bit Button is pin_b0
34
35 -- Led at pin_b4
36 var volatile bit LED is pin_b4
37
38
39 -- 1 millisecond wait procedure
40 -- TMR0_delay=(256-InitTMR0)*4*prescaler/Fosc
41 -- TMR0_delay=(256-6)*4*4/4_000_000= 1 msec.
42 --
43 -- InitTMR0 = 6
44 -- Prescaler = 1:4
45 -- Fosc = 4_000_000
46 --
47 -- Delay = 0.001 secs
48
49
50 -- Init TMR0, free run mode, int osc, prescaler 1:4
51 var volatile byte TMR0 at {0x01,0x101}
52 var volatile byte OPTION_REG at {0x81,0x181}
53 OPTION_REG = 0b_1000_0001
54
55 -- Disable interrupts, reset TMR0 flag
56 var volatile byte INTCON at {0x0B,0x8B,0x10B,0x18B}
57 var volatile bit T0if at INTCON : 2
58 INTCON = 0
59
60 const byte InitTMR0 = 6
61
62 procedure wait_1sec is
63 for 1_000 loop
64 -- Wait for TMR0 1 msec.
65 while ( ! T0if ) loop
66 end loop
67 -- Reset TMR0IF
68 T0if = low
69 -- Add InitTMR0
70 TMR0 = TMR0 + InitTMR0
71 end loop
72 end procedure
73
74
75 -- Reset PORTB
76 PORTB = 0b_0000_0000
77
78 -- PORTB => B0 input, B1..B7 output
79 TRISB = 0b_0000_0001
80 PORTB = 0b_0000_0001
81
82
83 -- main loop
84 forever loop
85 if ! Button then ; Check if Button is
86 ; permanently pressed
87 LED = on
88 wait_1sec
89 LED = off
90 wait_1sec
91 end if
92 end loop
- 1-36
- See Example 1 in section 4.2 1sec:Example-1:-Scan.
- 39-47
- Inline comments with a brief description how to set TMR0.
Take your PIC chip datasheets and read the section entitled TIMER
0. The goal in this example is to get a TMR0 overflow each millisecond.
Using a 4MHz crystal, it's necessary a prescaler of 1:4 and init TMR0
with a constant value each time it overflows.
- 50-58
- Declare and initialize the SFRs related with TMR0. See your
PIC chip datasheets, here TMR0 will work in free running mode.
- 62-72
- At this point TMR0 overflows each millisecond and will set
a bit called T0IF. The WHILE statement will stop program until T0IF
is set (TMR0 overflow), so we must reset this bit and load
TMR0 with the init constant value. Doing these steps 1000 times will
give us one second delay.
- 75-80
- See Example 1 in section 4.2 1sec:Example-1:-Scan.
- 83-92
- In this example the LED will blink only when Button
is kept pressed.
Next: 5 Example 4: Using
Up: 4 Examples
Previous: 3 Example 2: Control
Contents
pJAL Manual.
(c) 2006 Javier Martinez, Vasile Surducan and Dave Lagzdin.


We investigated the role of the WW domain-containing oxidoreductase ( wwox) gene in the embryonic development of zebrafish, with particular emphasis on intracellular Ca 2+ dynamics because Ca 2+ is an important intracellular messenger. Comparisons between zebrafish wwox and human WWOX sequences identified highly conserved domain structures. wwox was expressed in developing heart tissues in the zebrafish embryo. Moreover, wwox knockdown induced pericardial edema with similarities to conditions observed in human breast cancer. The wwox knockdown embryos with the edema died within a week. High Ca 2+ levels were observed at the boundary between the edema and yolk in wwox knockdown embryos.
WW domain-containing oxidoreductase ( WWOX) is a tumor suppressor gene that is reportedly absent in several cancers, including those of breast, prostate, and ovary ( Lewandowska et al., 2009; Salah, Aqeilan & Huebner, 2010), and has been associated with cancer progression in Wwox conditional knockout (KO) mice ( Yang & Zhang, 2008; Gardenswartz & Aqeilan, 2014; Li et al., 2014). WWOX is a 46-kDa protein with two N-terminal WW domains and a central short-chain dehydrogenase/reductase domain (SDR domain). These WW domains may be involved in protein–protein interactions, whereas the SDR domain may play roles in steroid metabolism and bone development ( Salah et al., 2013; Li et al., 2014). WWOX is essential for vertebrate development and bone metabolism, which are dependent on intracellular Ca 2+ levels ( Aqeilan et al., 2008). Accordingly, Ca 2+ signaling is known to be a key messenger in various biological phenomena ( Niki et al., 1996; Slusarski & Pelegri, 2007), and intracellular Ca 2+ levels are reportedly increased in advanced sarcoma ( Britschgi et al., 2013). However, it is difficult to monitor intracellular Ca 2+ levels in various developmental stages of mammals because their embryos are not transparent. Hence, we focused on zebrafish ( Danio rerio), which provides an established model to study human cancer and offers several advantages over mammalian model systems, including rapid development of transparent embryos ( Amatruda et al., 2002; Feitsma & Cuppen, 2008). In the present study, we investigated the function of wwox in vertebrate development using D. rerio as a model organism, and assessed the ensuing effects on intracellular Ca 2+ dynamics.
Adult wild-type zebrafish were purchased from a local pet store (Remix, Nagoya, Japan) and were maintained at 28.5 °C in 2-L tank equipped with a system that circulates conditioned filtered tap water under a 14-h/10-h light/dark cycle. Embryos were generated from natural crosses. Fertilized eggs were rinsed with autoclaved 1/3 Ringer’s solution containing 1.67 mM HEPES, 38.7 mM NaCl, 0.97 mM potassium chloride, and 0.60 mM calcium chloride (pH 7.2) to remove debris. Constructs of yellow cameleon 2.12 (pCS2-YC2.12) were kindly provided by A. Miyawaki (RIKEN Advanced Science Institute, Wako, Japan). The open reading frame of YC2.12 was inserted between BamHI and EcoRI restriction sites located downstream of the SP6 promoter sequence in the pCS2 vector. Using SP6 RNA polymerase from the mMessage mMachine SP6 in vitro transcription kit (Life Technologies, Carlsbad, CA, USA), 5′-capped YC2.12 mRNA was synthesized in vitro using pCS2-YC2.12 as a template. Synthesized mRNA from a single expected electrophoretic band was purified, dissolved in nuclease-free water, and stored at −80 °C before use. No approval was required to conduct studies on fish according to the Ministry of Education, Culture, Sports, Science and Technology, Notice No. 71 (in effect since June 1, 2006).
Total RNA was extracted from whole fish embryos at various developmental stages. After rinsing with 10 mM phosphate-buffered saline (PBS) at pH 7.4 (2.9 mM NaH
Target wwox cDNA was synthesized from total RNA (2.7 µg) using a SMART RACE cDNA Amplification Kit (Takara Bio, Shiga, Japan) and was amplified using an Advantage 2 PCR Kit (Takara Bio) with the following primers (accession no.
MOs (Gene Tools, LLC, Philomath, OR, USA) and siRNA (B-Bridge International, Inc., Tokyo, Japan) were used to knockdown the expression of wwox (accession number:
Microinjection needles were prepared from model GD-1 microcapillaries using a model PC-10 micropipette puller (Narishige, Tokyo, Japan). Embryos were placed in an agarose chamber and were soaked in 1/3 Ringer’s solution. Approximately 3 nL of synthetic mRNA (0.5 ng/mL) and siRNA (50 µM) were then injected into blastodiscs of each single-cell embryo. Subsequently, embryos were transferred to new dishes that contained the same medium and were incubated at 28.5 °C. Numbers of eggs were 2460 in wwox MO, 2590 in wwox siRNA, and 770 in rescue experiments. Positive yellow fluorescent protein (YFP) expression was detected in mRNA-injected embryos using a Leica L2 microscope equipped with a L5 FL Stereofluorescence System (Leica, Tokyo, Japan). Images were captured using a CoolSNAP cooled 5.0 charge-coupled device camera with RS Image Software (Roper Industries, Inc., Sarasota, FL, USA). Embryos were embedded in 3% methylcellulose (Sigma-Aldrich, St. Louis, MO, USA) to straighten their bodies, and body length images were measured from the head to the tail along with body axis in lateral view ( n = 30) in three independent experiments using RS Image Software. Eye sizes were measured and the longest diameters of eyeballs were recorded. Data are presented as means ± SEM, and differences between groups were identified using Student’s t-test and were considered significant when p < 0.01.
Embryos expressing YC2.12 mRNA were mounted in glass-bottom (0.08 mm) Petri dishes (35 mm; Matsunami Glass, Ind., Ltd., Osaka, Japan) that contained 1/3 Ringer’s solution supplemented with 3% methylcellulose. YC2.12 is a Förster resonance energy transfer-based indicator that exploits conformational changes following binding of calcium to the CaM motif, which alters the distance between the relative orientations of cyan fluorescent protein and YFP, and is reflected by energy transfer between the markers. Fluorescence was quantified as previously described ( Miyawaki et al., 1999; Tsuruwaka et al., 2007). Embryos at prim-15 stage (30 h post fertiliation; hpf) were analyzed because Ca 2+ imaging could not be performed after 33 hpf due to the remarkable pigment patterns on zebrafish bodies ( Tsuruwaka et al., 2007).
The wwox antisense probe 5′-TAAATGGACACTTGCGGGAATACAAACACT-3′ was obtained from Hokkaido System Science Co., Ltd. (Sapporo, Japan), and was labeled with DIG-11-UTP using a DIG Oligonucleotide Tailing Kit, 2nd Generation (Roche, Mannheim, Germany). Probe concentrations were estimated using an absorption spectrometer.
In these experiments, embryos were manually dechorionated, fixed overnight in 4% buffered paraformaldehyde (PFA) at 4 °C, dehydrated with a series of graded methanol (MeOH) solutions, and stored at −20 °C in MeOH for further use. After thawing, embryos were immersed in a series of 75%, 50%, and 25% MeOH solutions in PBS containing 0.1% Tween 20 (PBST; pH 7.0) for 5 min at room temperature (RT). Endogenous peroxidase activity was inhibited by incubation in 3% H
After hybridization, embryos were briefly washed in hybridization buffer (without tRNA and heparin), and were then washed in a gradient of hybridization buffer/2 × SSC of 75%/25%, 50%/50%, and 25%/75% at 55 °C for 30 min each, with a final wash in 100% 2 × SSC. Subsequently, embryos were washed two times in 2 × SSC for 30 min at RT, followed by a 10-min wash at RT over a gradient of 0.2 × SSC/PBST of 75%/25%, 50%/50%, and 25%/75%, and a final wash in 100% PBST. Embryos were then preabsorbed for 2 h at RT under slow agitation in antibody buffer comprising PBST, 2% sheep serum, and 2 mg/mL bovine serum albumin. Subsequently, embryos were incubated with Anti-Digoxigenin-Fluorescein Fab fragments (dilution, 1:1000; Roche) in antibody buffer overnight at 4 °C under gentle agitation according to the manufacturer’s protocol.
After antibody incubation, embryos were washed six times for 15 min each in PBST, and microscope analyses were performed on embryos mounted in glass-bottom dishes using a Zeiss Axiovert 200 fluorescence microscope (Carl Zeiss, Oberkochen, Germany).
Homology of zebrafish and human wwox sequences was assessed using sequences retrieved from the GenBank database (
(A) Human and zebrafish WWOX amino acid sequence alignments Human WWOX (accession no.
Injections of wwox targeting MOs into zebrafish embryos resulted in phenotypic alterations that were characteristic of pericardial edema at 48 hpf during the long-pec stage ( Fig. 2A). A similar phenotype was produced by siRNA knockdown during development ( Fig. 2B), with 56% and 62% penetrance of edema in 48 hpf embryos after injections with MOs and siRNA, respectively. Edema was particularly severe around the heart and caused death of embryos within 1 week. However, wwox mRNA rescued the phenotype in MO and siRNA injected embryos ( Figs. 2C and 2D). Knockdown of wwox caused noticeable reductions in eye sizes and body lengths, and embryos had twisted backbones ( Fig. 2E). The formation of edema was apparent from the segmentation period and a distinct phenotype was observed during the long-pec stage (data not shown). In subsequent fluorescence whole-mount in situ hybridization experiments, wwox expression was detected in developing hearts of zebrafish embryos, and was further visualized in tissue sections using in situ hybridization and immunocytochemical staining methods. Strong wwox expression was detected in developing hearts at 48 hpf and weak expression was observed in putative digestive organs ( Fig. 3A). Ventricles had higher wwox expression than atriums, and weak localized expression was detected in optic nerves ( Fig. 3B). Moreover, wwox expression became detectable from the prim-5 stage (24 hpf) and was clear at the prim-25 stage (36 hpf) during formation of the developing heart ( Fig. 3C).
Arrows indicate edema; (A) Upper, A bright-field image of a (i) wild-type embryo; (ii) wwox negative-control MO-injected embryo; and (iii) wwox MO-injected embryo; Lower, fluorescence image of the upper panel. (B) A wwox siRNA-injected embryo. (C) A wwox rescued MO-injected embryo (upper, bright-field image; lower, fluorescence image). (D) A wwox rescued siRNA-injected embryo. (E) Quantification of body lengths and eye sizes of long-pec embryos; 30 embryos were examined in three independent experiments and data are expressed as means ± SEM ( ∗∗ p < 0.01); WT, wildtype; Scale bars, 250 µm.
(A) Lateral view of the heart (upper) and tail (lower) of the embryo at the long-pec stage; Arrow, ventricle; arrow heads, putative digestive organs. (B) A cardiac tissue section of the long-pec embryo; Arrow heads show optic nerves. (C) Lateral view of embryos at prim-5 (upper) and prim-25 (lower); Arrows indicate putative ventricles; Scale bars, 250 µm.
Inhibition of wwox expression caused morphological abnormalities, and Ca 2+ signaling patterns are reportedly altered during zebrafish morphogenesis ( Tsuruwaka et al., 2007; Webb & Miller, 2007). Therefore, we analyzed intracellular Ca 2+ dynamics after edema formation in embryos that had been simultaneous transfected with yellow cameleon, YC2.12, and siRNA. Patterns of Ca 2+ dynamics strikingly differed between wwox knockdown embryos and normal fish ( Fig. 4), with maximal Ca 2+ levels at the boundary between the edema and yolk.
Upper, bright field image; lower, color-coded image; (A) wildtype; (B) wwox knockdown produced edema formation and induced altered Ca 2+ dynamics; Scale bars, 250 µm. The color-coded image shows Ca 2+ levels as white (high Ca 2+) and blue (low Ca 2+).
Relatively high rates of intracellular Ca 2+ dynamics were observed among areas of heart tissue and in putative digestive organs that expressed wwox. High Ca 2+ levels were observed in putative digestive organs, but no corresponding morphological changes were noted.
Human WWOX has been functionally associated with breast cancers in humans, and zebrafish and human WWOX amino acid sequences are highly homologous. Thus, despite the absence of breast tissue in zebrafish, zebrafish and human WWOX may have similar functions. In the present study, knockdown of wwox in zebrafish embryos produced a pericardial edema phenotype.
Nunez, Ludes-Meyers & Aldaz (2006) reported high WWOX mRNA expression in human breast, ovaries, testes, and prostate tissues, and WWOX expression was reportedly absent in several breast cancers ( Lewandowska et al., 2009). Although zebrafish do not possess mammary tissues such as those in humans, edema formation was observed around the pectoral region in wwox deficient zebrafish, as shown in mice ( Qu et al., 2013). Previous studies implicate WWOX in the development of gastric carcinoma ( Aqeilan et al., 2004), suggesting that additional effects of wwox dysregulation may be associated with the present zebrafish phenotype. Accordingly, high levels of Ca 2+ were observed in tissues with high wwox expression, with the exception of the dorsal region, which was subject to deleterious digestive tract and blood vessel environments that reflected dysfunctions of the heart pump. Analyses of Ca 2+ dynamics in wwox knockdown zebrafish suggested novel roles of dorsal–posterior regions other than the pericardial edema. Specifically, wwox knockdown embryos displayed early lethality that was similar to that in Wwox KO mice, which died by 4 weeks of age ( Aqeilan et al., 2007). Other phenotypes observed in Wwox KO mice included abnormal bone structures and reduced postnatal growth ( Ludes-Meyers et al., 2009). Developmental retardation, as indicated by small eyes and heads and abnormal bone formations, was also observed in wwox knockdown zebrafish embryos. Similarly, postnatal day 18 Wwox KO mice showed notable differences in bone structure, with significantly decreased bone volume and cortical thickness compared with wild-type mice. Moreover, a Wwox gene mutation ( lde) was identified in rats and led to phenotypic lethal dwarfism with epilepsy ( Suzuki et al., 2009). These defects in bone formation further suggest that wwox knockdown alters Ca 2+ dynamics. In a previous study, Webb & Miller (2007) showed that Ca 2+ signaling changes with somite formation during zebrafish development. Moreover, alterations of Ca 2+ dynamics at various sites suggest that multiple organ failure have led to death in the present embryos.
In summary, we demonstrated the utility of the present fish model in studies of wwox gene function. The present data show strong effects of wwox knockdown in developing heart tissue and weaker effects on putative digestive organs. Subsequently, high Ca 2+ levels were observed at ventral–dorsal–posterior regions along with the blood circulation of wwox knockdown zebrafish embryos. Therefore, inhibition of wwox could have pointed a non-cell-autonomous phenotype. These data suggest roles of wwox in multiple tissues during fish embryonic development, as previously reported in mice. In morphological studies, inhibition of wwox expression led to edema formation, resembling that previously shown in developing tumors ( Jiang & Hui, 2008). Finally, abnormal Ca 2+ dynamics were observed after inhibition of wwox expression, suggesting that monitoring of Ca 2+ levels may provide an additional indicator for phenotype analyses. However, further studies are required to determine whether the present zebrafish edema was derived from carcinogenic processes.
Zebrafish wwox was expressed highly in developing heart tissues and detectably in putative digestive organs. Loss of wwox function caused edema in the pectoral region, developmental retardations such as small eyes and short body lengths, and altered Ca 2+ dynamics.
We wish to thank Dr. Atsushi Miyawaki for providing the YC2.12 construct and Dr. Takafumi Konishi for his helpful advice.
The authors declare there are no competing interests.
Yusuke Tsuruwaka conceived and designed the experiments, performed the experiments, analyzed the data, contributed reagents/materials/analysis tools, wrote the paper, prepared figures and/or tables, reviewed drafts of the paper.
Masataka Konishi performed the experiments.
Eriko Shimada performed the experiments, analyzed the data, wrote the paper, reviewed drafts of the paper.
The following information was supplied relating to ethical approvals (i.e., approving body and any reference numbers):
No approval was required to conduct studies on fish according to the Ministry of Education, Culture, Sports, Science and Technology, Notice No. 71 (in effect since June 1, 2006).
The following information was supplied regarding the deposition of DNA sequences:
GenBank accession no.


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Considering projects
for Q3, 2015.
Jan 2015
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Derek Peruo
Front-End Architecture and Development
New York, NY, USA
+1<PHONE_NUMBER>
<EMAIL_ADDRESS>derekperuo.net/playbook
~ Currently: {{::header.currentEvent}} ~
TEACHING
CSS Preprocessors
Programming Languages
EDUCATION
Chicago, IL, USA
Aug 2004 – Jun 2008
DePaul University
BFA, Theatre and Performance
LANGUAGE
English (native)
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INFLUENCIAL BOOKS
Tao of Pooh
Ender's Game
4-Hour Workweek
On the Shortness of Life


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accept(String)
- Method in class views.etat.
Administrator
Accept.
acceptableValue
- Variable in class model.
Feature
The acceptable value.
action(String[])
- Method in class views.
State
Action.
add(String)
- Method in class views.etat.
Borrow
Adds the.
add(String, String, String)
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Find
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addBorrow(Borrower.Borrow)
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Inventory
Adds the borrow.
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Inventory
Adds the equipment.
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Administrator
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addFeatureById(String, String, String)
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Inventory
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addFeatureById(String, String, String)
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Adds the feature by id.
Administrator
- Class in
model.person
The Class Administrator.
Administrator(String, String, String)
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Administrator
Instantiates a new administrator.
Administrator
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views.etat
The Class Administrator.
Administrator()
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Administrator
ADMINISTRATOR_ID
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SaveLoad
The Constant ADMINISTRATOR_ID.
administratorId
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Borrower.Borrow
The administrator id.
args
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Command
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ArrayUtils()
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Library Redesign - Case Study Preview
The full case study (with additional details and pictures) is password protected due to an NDA.
Email me at<EMAIL_ADDRESS>for the password.
Password
PresenceLearning is an online special education therapy platform where special education therapists or "providers" connect with students with special needs via video calls to help them achieve their goals.
Providers contract with PresenceLearning and remotely connect with students to help schools meet their special education needs.
Writing user research plan
Conducting usability tests
Documenting research and test findings
Compiling user feedback
The Library is where special education therapists can find activities, like worksheets and videos, to use with their students with special needs in the Virtual Therapy Room.
Access to the content library is a large selling point for the product, but had a lot of room for improvement.
We started a redesign of the Library to address its usability issues and improve a core part of the platform.
Summary of what I did for this project:
- I talked to our clinical team to better understand the Library and how it's used.
- I reviewed relevant user feedback from various internal sources.
- I defined user end goals (alongside the expert clinical team) to give direction for the redesign efforts.
- I measured the existing design against the user end goals to evaluate its effectiveness and expose areas of improvement.
- I explored various designs in low-fidelity and created an interactive prototype of an improved version of the Library for testing.
- I ran usability tests with special education therapists to validate the design and understand the highest impact items for development.
- I created a high-fidelity prototype with components from Material Design, Google's design system that the company is adopting for newer projects.
- I established a process for usability testing designs and documented the procedures for the rest of the team. Usability testing is now integrated the design process.
- I defined a visually accessible Material Design theme to ensure a consistent visual style as the company adopts Material.
- I compiled relevant customer feedback from various sources into a single document as a resource for the team.


Grocer Pano:
Ah yes, the Gold Dragon. Shall we trade? I will trade you one Gold Dragon for 5 Gold Wyrms and 5 Gold Giants. Or perhaps you would prefer a game of chance?
Accept the regular exchange rate
Play game. [Guess correctly in 2 tries - 4 Gold Giants]
Play game. [Guess correctly in 3 tries - 8 Gold Giants]
Play game. [Guess correctly in 4 tries - 9 Gold Giants]
Explanation of game


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| DOSE: T+ 0:00 |
1 hit |
oral |
LSD |
(blotter / tab) |
| T+ 1:00 |
1 hit |
oral |
LSD |
(blotter / tab) |
| T+ 1:00 |
2 hits |
smoked |
Salvia divinorum |
(extract) |
| T+ 1:00 |
2 hits |
smoked |
DMT |
(extract) |
Let me take a timid peak
Into deaths
Other kingdom
How is one suppose to describe the indescribable? There is truly no way I could ever account to anyone what truly happened.
Iíve done drugs before. I am very experienced with acid, enjoy shrooms and DMT, and have used Salvia on a number of special occasions. I found that even though DMT is amazingly intense and powerful, I can still keep some perspective of what is happening. even in a full blown DMT hyperspace journey I find that there is some nerve in my mind still connected to reality. This does not apply to salvia. I have lost myself in salvia before, an experience I am both eager to do again and yet I am terrified beyond all belief at the sheer intensity of the experience.
I have done a LSD and DMT mix before, to profound and utterly mind blowing results. and on one other occasion I smoked both Salvia and DMT together. It was tricky at first. I had to have enough salvia on top of the DMT crystals in order to protect them from the open flame. I think deep but narrow bowls work best for this. The heat of the flame will vaporize the DMT while burning w/e is on the surface.
Anyhow I stared things off by coming to the realization that I wanted to go somewhere I doubt many people go. What would happen to one if they unleashed the three most powerful psychedelics known to man on their own mind. Would they snap? Self destruction would be a likely possibility.
Anywho I put my fears away and embraced this as some sort of spiritual orgasm in which I will ride all the way to the almighty peak and back. First things first, I needed the acid, lots of it. Then I needed some DMT, an easy thing to do in California at 5 forty 4 on a warm Saturday midway into the summer. But salvia was tricky. Odd, seeing that it was the only legal substance in the list, and I couldnít find any, a number of websites wouldnít ship to California, and the only too known headshops werenít equipped with the drug. Anyhow I ran into a 'sub'friend who had a gram of salvia 15x. very potent.
I arranged for a good friend to sit with me. He would remain somewhat sober, avoiding the acid and sticking to good marijuana.
I think ill skip all the preparations. all thatís necessary is I had a pre made and specially arranged mix of salvia and DMT already prepared for me and already packed in a bowl (in a bong). I thought I could probably get a good two rips before I was completely twisted.
The acid was medium in strength, and after one hour of riding out one hit I decided that if I was to do things they must be done right. So I dropped another blotter. That did the trick. The waves and spider web thoughts were intense, the patterns and visuals were of profound beauty: it was time.
We were in my room of my apartment, a warm comfortable place. I propped myself up on my couch and my bud held the bong and lighter for me. I positioned it and held the carb shut. I gave him the signal and he began to light the mix as I took my first rip. it was long, and I held it for a good fifteen seconds. As I exhaled I could slowly feel the rushing sensation of the DMT pronounce itself at the same time the odd 'salvia gravity' sensation became noticeable. I knew that in order for me to break through I needed to take a monster rip, and I needed to hold it. So thatís what I did. I dragged that fucker for the longest time, advising my friend to hold the lighter a little further away from the mix so that the flame wouldnít touch the DMT crystals arranged at the bottom of the bowl. the salvia extract started making funny sounds as it burned.
 I never exhaled. My friend said that I closed my eyes and entered a trance as I fell back onto the couch. Good thing he was there or I would of dropped the bong.
let us peak
into deaths
other dream kingdom
'and alice followed the rabbit down into the rabbit whole..'
jjjjjjjjjjjkkkkkkkkkkkkkkkk jjjjjjjjj kkkkkkkkkk
*&*&^&**&^^*&
?!?!?!?!?!?!?!?!?!?!?CC
and that is C minus four
z?
no
D?
no
8?
yes.
eight what?
bannas
what was happening?
it took me a while to figure out what I was seeing.
I still cant quite say.
some say it was a mass of needles
I was looking for the hay
the needles all smiled
werenít that bad in the end
I was stuck without reality
the goose without his friend
I was peaking over from the edge of some great peak of (mountains? Or was it the warted body of some massive toad..) Something, looking at what seemed to be a pulsating valley.  I wasnít sure of what I was seeing. I wasnít sure what it was.
It was a valley, incredibly real, yet it seemed to spiral out in front of me like some, well, big spiral. The valley walls stayed still but the matter of which they were made of seemed to be sliding and melting. as I stared at the valley I saw it elongate and slowly I took off. Was I peaking? wasnít I already at the peak?
Idk where I went. The valley lost all shape and form and simply became something else. it was some sort of warped tube at which I was traveling down at amazing speeds, invincible to all aspects or forces of nature. Suddenly, I know because before it happened I could feel that I was about to take a step to places no one had been to, suddenly I detached. The best way to describe it is that what I thought was the peak was magnified ten fold, and I lost it. The trip itself became the reality at which I was judging the current reality on. Normal wasnít what I was when I was baseline, normal was now defined as the first thirty seconds of the trip. What I had just entered was a place beyond time.
The spiral went white, and what I saw was a white space. Sort of like a negative shot of the space we have come to know. What should of been glowing stars were big balls of black matter. I think I looked down at my feet and realized that this whiteness was infinite. Spaced fairly evenly throughout this white space were the big balls. At first they seemed alien, then they became somewhat more placid, a little crispy, too much pepper, then suddenly all the balls exploded in vibrant colors and once again I was rushing. The DMT was coming in hard, what had taken it so long?   The stars were indeed stars.
Then I blacked out. I canít remember anything clearly after that, too intense.
What I can remember was one thing. At some point I was very high in space, I was 'close' to the edge of space. If I was to reach out with my arm I would exit space and enter the beyond. It was then I saw the great machine, the interworkings of the universe. It was literally a great machine. I had turned away from the edge of space and was looking down at everything, and hot damn it was a machine of which the knobs and levers on it were of sizes unheard of. I donít know why this single image of the peak has stayed with me while most of everything else has simply faded into one astonished wow.
It was like my mind took one desperate snap shot of the single highest point during the trip, and that is all I have to hold onto, the last fragments of something so amazing. there is really no way I could describe the feeling that I was part of that machine, yet even though I already new that my part to play in the machines workings was planned out, I could see that I didnít have to follow those rules. What would happen if I strayed? Chaos.
The very last memory of the peak I have is of looking at the machine and realizing that it was breathing, then, well, I donít quite know. Perhaps the peak continue to grow, perhaps I entered the beyond. What happened still clouds me, two days after the experience. Perhaps a few hours of meditating will bring back what happened.
All I know is that when I opened my eyes and saw a mass of pink pixels staring at me I was amazed that it seemed so ordinary. As I came back to acid baseline I swore that this was real and that I am finally normal. Thatís how high I was folks, so high that when I came off the DMT/Salvia mix the acid seemed mundane. I was amazed.
I then began to go dance in an effort to try to explain to my friend what happened. After that I simply sat down and enjoyed the acid as it did odd things with my carpet. Idk if it was some lingering side effect of the previously consumed combo, but I could swear that all the patterns I was seeing afterwards were somehow magnified and intensified. Even two hours after I had blazed and was slowly coming off the acid I could swear that the patterns and visuals were more 'real' than they should of been. Didnít bother me though, it gave me a feeling that I had been left with something from that experience
I donít think ill ever understand what happened there is no way I could really describe the utter horror/fear/amazement/aw at what happened. I think the best way to put it is that I had sex with my mind.    Will I ever do it again? yes, I probably will. it was so amazing that I think I will prob have to live it again.
 But fuck, why do people ride roller coasters anyways?
Experience Reports are the writings and opinions of the individual authors who submit them.
Some of the activities described are dangerous and/or illegal and none are recommended by Erowid.