Datasets:
sequence stringlengths 4 17.9k | seq_id stringlengths 1 6 | pn stringclasses 996
values | title stringclasses 871
values | pbdt int64 20.2M 20.3M | status int64 1 225 ⌀ | family_country listlengths 1 55 | modified_info stringlengths 112 8.31k ⌀ |
|---|---|---|---|---|---|---|---|
atcacacgcacacacaaaagaag | 1239 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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] | null |
atcacacgcacacacaaaagaag | 1239 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | null |
atcacacgcacacacaaaagaag | 1239 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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atcacacgcacacacaaaagaag | 1509 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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atcacacgcacacacaaaagaag | 1509 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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atcacacgcacacacaaaagaag | 1509 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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aagccttttgctcacaaaaca | 2838 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
aagccttttgctcacaaaaca | 2838 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
aagccttttgctcacaaaaca | 2838 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
aagccttttgctcacaaaaca | 2572 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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"EA",
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] | null |
aagccttttgctcacaaaaca | 2572 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | null |
aagccttttgctcacaaaaca | 2572 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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] | null |
aagccttttgctcacaaaaca | 2074 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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"NZ",
"EA",
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
aagccttttgctcacaaaaca | 2074 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
aagccttttgctcacaaaaca | 2074 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
aagccttttgctcacaaaaca | 1806 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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] | null |
aagccttttgctcacaaaaca | 1806 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | null |
aagccttttgctcacaaaaca | 1806 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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"CA",
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] | null |
aagagaaccagaaacaatgccag | 900 | JP2024535850A | 補体成分(C3)をサイレンシングするためのiRNA組成物および方法 | 20,241,002 | 2 | [
"JP",
"US",
"WO",
"EP"
] | null |
aagagaaccagaaacaatgccag | 834 | JP2024535850A | 補体成分(C3)をサイレンシングするためのiRNA組成物および方法 | 20,241,002 | 2 | [
"JP",
"US",
"WO",
"EP"
] | null |
tctgtcaactgcaccatgcattt | 2007 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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] | null |
tctgtcaactgcaccatgcattt | 2007 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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"IN",
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"EP",
"WO",
"HK",
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"ZA",
"CA",
"KR"
] | null |
tctgtcaactgcaccatgcattt | 2007 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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"EP",
"WO",
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"CA",
"KR"
] | null |
tctgtcaactgcaccatgcattt | 2944 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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"EA",
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
tctgtcaactgcaccatgcattt | 2944 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
tctgtcaactgcaccatgcattt | 2944 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
tctgtcaactgcaccatgcattt | 2678 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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"CA",
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] | null |
tctgtcaactgcaccatgcattt | 2678 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | null |
tctgtcaactgcaccatgcattt | 2678 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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] | null |
tctgtcaactgcaccatgcattt | 2275 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
tctgtcaactgcaccatgcattt | 2275 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
tctgtcaactgcaccatgcattt | 2275 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyluridine-3'-phosphorothioate 5'-(E)-Vinylphosphonate","norInfo":[{"modificationType":"Non natural base","modification":["um"]},{"modificationType":"Chemical","modification":["Phosphorothioate"]}]}],"locations":["1->1"... |
aagaaatgttaagctcttctt | 1396 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
aagaaatgttaagctcttctt | 1396 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
aagaaatgttaagctcttctt | 1396 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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aagaaatgttaagctcttctt | 1129 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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"WO",
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] | null |
aagaaatgttaagctcttctt | 1129 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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"CA",
"KR"
] | null |
aagaaatgttaagctcttctt | 1129 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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] | null |
aagtcccggcggctcttccaa | 764 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
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] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
aagtcccggcggctcttccaa | 764 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
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aagtcccggcggctcttccaa | 764 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
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"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methyladenosine-3'-phosphorothioate","norInfo":[{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos":["OTHER","2'-O-methyladenosine-3'-phosphorothioate"]},{"norI... |
aagtcccggcggctcttccaa | 494 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
aagtcccggcggctcttccaa | 494 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
aagtcccggcggctcttccaa | 494 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
gagctggcaaaggtggctcta | 1913 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
gagctggcaaaggtggctcta | 1913 | EP4416284A1 | EXTRAHEPATISCHE IRNA-ZUSAMMENSETZUNGEN ZUR ABGABE UND VERFAHREN ZUR VERWENDUNG DAVON | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
gagctggcaaaggtggctcta | 1913 | EP4416284A1 | COMPOSITIONS D'ARNI À ADMINISTRATION EXTRA-HÉPATIQUE ET LEURS PROCÉDÉS D'UTILISATION | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | null |
gagctggcaaaggtggctcta | 2765 | EP4416284A1 | Extra-hepatic delivery irna compositions and methods of use thereof | 20,240,821 | 1 | [
"JP",
"NZ",
"EA",
"SG",
"CN",
"MX",
"AU",
"IN",
"US",
"EP",
"WO",
"HK",
"IL",
"ZA",
"CA",
"KR"
] | [{"norInfos":[{"sourceData":"OTHER","norInfo":[{"modificationType":"Other"}]},{"sourceData":"2'-O-methylguanosine-3'-phosphorothioate","norInfo":[{"modificationType":"Non natural base","modification":["gm"]},{"modificationType":"Chemical","modification":["Phosphorothioate","2'-O-methyl"]}]}],"locations":["1->1"],"infos... |
End of preview. Expand in Data Studio
🧬 Dataset Summary
Patent-linked nucleotide sequence records focused RNAi therapeutics patent portfolio. Each record pairs a raw nucleotide sequence with its source patent number, publication date, and global patent family coverage.
🚀 Key Features
- Patent Linkage: Each sequence is tied to a patent number (
pn) and publication date (pbdt), enabling sequence-to-IP traceability. - Global Family Coverage:
family_countrylists all jurisdictions in the patent family (e.g., US, EP, CN, JP, WO). - Patent Status:
statusfield tracks the current patent lifecycle state. - Modification Tracking:
modified_infocaptures amendment history where available (~8.6% of records).
💻 Quick Start & MCP Integration
from datasets import load_dataset
dataset = load_dataset("your-org/alnylam-sequences", split="train")
print(dataset[0]["sequence"])
# Output: 'atcacacgcacacacaaaagaag'
print(dataset[0]["pn"])
# Output: 'EP4416284A1'
print(dataset[0]["family_country"])
# Output: ['JP', 'NZ', 'EA', 'SG', 'CN', 'MX', 'AU', 'IN', 'US', 'EP', 'WO', 'HK', 'IL', 'ZA', 'CA', 'KR']
🔗 Resources
- Developer Portal: open.patsnap.com
- PatSnap Life Sciences: patsnap.com/solutions/life-sciences
- GitHub: github.com/patsnap
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