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10.5114/aoms.2015.53289
Systematic review/Meta-analysis The role of gender in patients with diffuse large B cell lymphoma treated with rituximab-containing regimens: a meta-analysis
Diffuse large B cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma (NHL). Although gender has not been included in prognostic systems, male gender has been found as a bad prognostic indicator in Hodgkin lymphoma, follicular lymphoma and chronic lymphocytic leukemia. The relationship between gender...
[ { "section_content": "age, performance score, stage, proliferation fraction and gene expression profiles [3, 4]. Today, the International Prognostic Index (IPI) and age-adjusted International Prognostic Index (aaIPI) are the most important scores used in daily practice to determine the prognosis and treatment s...
[ { "section_content": "", "section_name": "Conflict of interest", "section_num": null }, { "section_content": "The authors declare no conflict of interest.", "section_name": "Conflict of interest", "section_num": null }, { "section_content": "", "section_name": "R e f e r e n ...
10.31557/apjcp.2022.23.9.3229
Interleukin-10-1082A>G (rs1800896) Single Nucleotide Polymorphism is Not a Risk Factor of Chronic Lymphocytic Leukemia in Sudanese Population
Objectif : La présente étude a été menée pour examiner l'association entre le polymorphismeIL-10-1082A >G (rs 1800896) et le risque de leucémie lymphoïde chronique et pour évaluer la corrélation entre ce polymorphisme et les caractères clinicopathologiques. Méthodes : Une étude cas-témoins a été menée dans l'État de Kh...
[ { "section_content": "Chronic lymphocytic leukemia is characterized by the progressive accumulation of monoclonal, small, mature-appearing CD5 + B-cells in the peripheral blood, bone marrow, and secondary lymphoid tissue (Caligaris-Cappio and Hamblin, 1999). Genetic variation of some immunomodulatory cytokine m...
[ { "section_content": "", "section_name": "Acknowledgments", "section_num": null }, { "section_content": "We would like to thank the staff of the Hematology Department at Al Neelain University for facilities and supporting and we are grateful to the staff of Flow Cytometry Laboratory for Leukemia...
10.3892/ijo.2012.1528
Epimutation and cancer: A new carcinogenic mechanism of Lynch syndrome
Epimutation is defined as abnormal transcriptional repression of active genes and/or abnormal activation of usually repressed genes caused by errors in epigenetic gene repression. Epimutation arises in somatic cells and the germline, and constitutional epimutation may also occur. Epi...
[ { "section_content": "", "section_name": "Recommendation", "section_num": null }, { "section_content": "", "section_name": "Reasons for Recommendation", "section_num": null } ]
[ { "section_content": "", "section_name": "Additional Comments", "section_num": null }, { "section_content": "Submission of this form allows Spandidos Publications to contact your institution regarding this recommendation. If you do not want Spandidos Publications to contact your institution, thi...
10.7554/elife.98747.3
The Jag2/Notch1 signaling axis promotes sebaceous gland differentiation and controls progenitor proliferation
<jats:p>The sebaceous gland (SG) is a vital appendage of the epidermis, and its normal homeostasis and function is crucial for effective maintenance of the skin barrier. Notch signaling is a well-known regulator of epidermal differentiation, and has also been shown to be involved in postnatal maintenance of SGs. Howeve...
[ { "section_content": "The skin is a vital organ that acts as a protective barrier against the external environment, and safeguards against fluid loss. An important component of this barrier function is the presence of a complex mixture of oils, known as sebum, which is produced by the SGs. SGs are part of the e...
[ { "section_content": "", "section_name": "Acknowledgements", "section_num": null }, { "section_content": "We are grateful to C Cottonham, S Hankeova, and G Hernandez for their helpful discussions. We thank the Genentech Research Pathology, Necropsy, and Histology laboratories for their experimen...
10.1186/s13000-017-0634-3
Detection of 22 common leukemic fusion genes using a single-step multiplex qRT-PCR-based assay
Fusion genes generated from chromosomal translocation play an important role in hematological malignancies. Detection of fusion genes currently employ use of either conventional RT-PCR methods or fluorescent in situ hybridization (FISH), where both methods involve tedious methodologies and require prior characterizatio...
[ { "section_content": "Fusion genes are genetic chromosomal aberrations formed by the juxtaposition of two disparate gene loci through chromosomal translocation, interstitial deletion, or inversion and is most frequently detected through cytogenetic abnormalities. Although hundreds of fusion genes have been asso...
[ { "section_content": "", "section_name": "Acknowledgements", "section_num": null }, { "section_content": "Not applicable.", "section_name": "Acknowledgements", "section_num": null }, { "section_content": "", "section_name": "Funding", "section_num": null }, { "sec...
10.1038/s41467-024-46547-7
Accelerated DNA replication fork speed due to loss of R-loops in myelodysplastic syndromes with SF3B1 mutation
<jats:title>Abstract</jats:title><jats:p>Myelodysplastic syndromes (MDS) with mutated <jats:italic>SF3B1</jats:italic> gene present features including a favourable outcome distinct from MDS with mutations in other splicing factor genes <jats:italic>SRSF2</jats:italic> or <jats:italic>U2AF1</jats:italic>. Molecular base...
[ { "section_content": "term treatment [6] [7] [8]. Deciphering the mechanisms of anemia is needed to generate treatments. \n\nSF3B1 mutation causes multiple alterations in mRNA processing. The use of alternative 3′ or 5′ splice site produces transcripts containing short intronic sequences that are degraded by th...
[ { "section_content": "", "section_name": "Acknowledgements", "section_num": null }, { "section_content": "The authors dedicate this work to the memory of their colleague Dr Angelos Constantinou whose discoveries inspired this work. The authors acknowledge Pr Seishi Ogawa ( Kyoto University, Japa...
10.1186/2045-824x-3-17
Therapeutic promise and challenges of targeting DLL4/NOTCH1
DLL4-mediated NOTCH1 signaling represents an essential pathway for vascular development and has emerged as an attractive target for angiogenesis-based cancer therapies. However, newly reported toxicity findings raise safety concerns of chronic pathway blockade. Lessons learned from the development of γ-secretase inhibi...
[ { "section_content": "In metazoans, the evolutionarily conserved NOTCH pathway functions as an essential mechanism to regulate numerous cell fate/lineage decisions during embryogenesis, postnatal development, and in the maintenance of adult tissue homeostasis. NOTCH receptors are normally constrained in a dorma...
[ { "section_content": "", "section_name": "Acknowledgements", "section_num": null }, { "section_content": "The author would like to thank Weilan Ye, Jessica Couch and Kevin Leong for valuable suggestions and critical reading of the manuscript.", "section_name": "Acknowledgements", "sectio...
10.18632/oncotarget.13712
"Humoral immune responses toward tumor-derived antigens in previously untreated patients with chroni(...TRUNCATED)
"In chronic lymphocytic leukemia (CLL) the occurrence and the impact of antibody responses toward tu(...TRUNCATED)
[{"section_content":"Immune dysfunctions are a key feature of chronic lymphocytic leukemia (CLL) and(...TRUNCATED)
[{"section_content":"","section_name":"CONFLICTS OF INTEREST","section_num":null},{"section_content"(...TRUNCATED)
10.1371/journal.pone.0004434
"Tumorigenic Potential of Olfactory Bulb-Derived Human Adult Neural Stem Cells Associates with Activ(...TRUNCATED)
"Multipotent neural stem cells (NSCs) have been isolated from neurogenic regions of the adult brain.(...TRUNCATED)
[{"section_content":"Due to their ability to self-renew and to differentiate towards the neuronal ph(...TRUNCATED)
[{"section_content":"","section_name":"Acknowledgments","section_num":null},{"section_content":"We t(...TRUNCATED)
10.1038/s41467-018-04283-9
NOTCH-mediated non-cell autonomous regulation of chromatin structure during senescence
"<jats:title>Abstract</jats:title><jats:p>Senescent cells interact with the surrounding microenviron(...TRUNCATED)
[{"section_content":"ellular senescence is an autonomous tumour-suppressor mechanism that can be tri(...TRUNCATED)
[{"section_content":"","section_name":"Acknowledgements","section_num":null},{"section_content":"We (...TRUNCATED)
End of preview. Expand in Data Studio

SciLake Fulltext Corpus

The SciLake Fulltext Corpus is a collection of scientific papers parsed and segmented by section, primarily designed for research in the development and evaluation of NLP models. This dataset contains 1,000 full-text papers from various scientific domains, including Neuroscience, Cancer, Transport, and Energy, along with an additional 5,000 random papers from general scientific domains. All papers have been curated with licenses that allow for legal usage, specifically CC-BY and Public Domain.

The dataset provides detailed metadata and full-text sections, offering a robust resource for domain-specific and general scientific research, dataset annotation, model training, and evaluation.

Corpus Overview

  • 1,000 Full-Text Papers Segmented by Section:
    • Domain-specific sections: Neuroscience 🧠, Cancer 🦀, Transport 🛻, Energy 🪫.
    • Each paper is segmented into sections such as Introduction, Methods, Results, etc.
  • 5,000 Random Papers from General Scientific Domains:
    • Mix of stratified sampled by MAG level 0 to ensure diversity across multiple domains and disciplines, and random sample.

Example of Dataset Structure:

{
'doi': DOI,
'title': TITLE,
'description': ABSTRACT,
'fulltext_sections': [
        {
            'section_name': SECTION_NAME_1,
            'section_num': SECTION_NUM_1,
            'section_content': SECTION_CONTENT_1,
        },
        ...
],
'fulltext_additional': [
        {
            'section_name': SECTION_NAME_1,
            'section_num': SECTION_NUM_1,
            'section_content': SECTION_CONTENT_1,
        },
        ...
]

How to use

from datasets import load_dataset

dataset_ds = load_dataset("SIRIS-Lab/scilake-fulltext-corpus")

Licensing Information

The SciLake Fulltext Corpus is released under the following licenses:

CC-BY (Creative Commons Attribution), licenses have been obtained from the publisher’s landing page, PDFs, metadata in OpenAire, and Unpaywall, filtering fro those with license CC-BY or Public Domain.

Dataset Acquisition

The papers included in this dataset were sourced through the OpenAIRE index, with random selection to ensure diverse content. The license information was verified by cross-referencing the publisher’s landing pages, metadata from OpenAire, and the Unpaywall database. Papers were retained if they had a CC-BY license or were in the Public Domain.

Funding

This work was partially funded by a projects under EU’s HORIZON Research and Innovation Programme:

  • SciLake (grant agreement No 101058573).

Contact

For more information, or if you have questions, please contact us at sirislab[at]sirisacademic.com.

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